Evidence map›Paper›PMID 37624801›Full record

ArticlePloS one2023

Teaching hospitals and their influence on survival after valve replacement procedures: A retrospective cohort study using inverse probability of treatment weighting (IPTW).

Kevin Maldonado-Cañón, Giancarlo Buitrago, Germán Molina, Francisco Mauricio Rincón Tello, Javier Maldonado-Escalante

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kevin Maldonado-CañónFacultad de Medicina, Instituto de Investigaciones Clínicas, Universidad Nacional de Colombia, Bogotá, Colombia.ORCID 0000-0003-1649-5290
Giancarlo BuitragoFacultad de Medicina, Instituto de Investigaciones Clínicas, Universidad Nacional de Colombia, Bogotá, Colombia.
Germán MolinaDepartment of Cardiovascular Surgery, Clínica Universitaria Colombia, Bogota, Colombia.
Francisco Mauricio Rincón TelloDepartment of Cardiovascular Surgery, Hospital Universitario Fundación Santa Fe de Bogotá, Bogota, Colombia.
Javier Maldonado-EscalanteDepartment of Cardiovascular Surgery, Clínica Universitaria Colombia, Bogota, Colombia.ORCID 0000-0003-3011-4650
Fundación Santa Fe de Bogotá · COUniversidad Nacional de Colombia · COFundación Universitaria Sanitas · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effect of teaching hospital status on cardiovascular surgery has been of common interest in recent decades, yet its magnitude on heart valve replacement is still a matter of debate. Given the ethical and practical unfeasibility of randomly assigning a patient to such an exposure, we use the inverse probability of treatment weighting (IPTW) to assess this marginal effect on the survival of Colombian patients who underwent a first heart valve replacement between 2016 and 2019.

methodsA retrospective cohort study was conducted based on administrative records. The time-to-death event and cumulative incidences of death, readmission, and reoperation are presented as outcomes. An artificial sample is configured through IPTW, adjusting for sociodemographic variables, comorbidities, technique, and intervention weight.

resultsOf a sample of 3,517 patients, 1,051 (29.9%) were operated on in a teaching hospital. The median age was 65.0 (18.1-91.5), 38.5% of patients were ≤60, and 6.9% were ≥80. The cumulative incidences of death at 30, 90 days, and one year were 5.9%, 8%, and 10.9%, respectively. Furthermore, 23.5% of the patients were readmitted within 90 days and 3.6% underwent reintervention within one year. The odds of 30-day mortality are lower for patients operated in a teaching hospital (OR 0.51; 95% CI 0.29-0.92); however, no effect on survival was identified in terms of time-to-event of death (HR 1.07; 95%CI 0.78-1.46).

conclusionsAfter IPTW, the odds of 30-day mortality are lower for patients operated in a teaching hospital. There was no effect on survival, 90-day or one-year mortality, 90-day readmission, or one-year reintervention. Together, we offer an opening for investigating an exposure that has yet to be explored in Latin America with potential value to understand teaching hospitals as the essential nature of reality of an academic-clinical synergy.

Indexed as

Hospitals, TeachingAgedCohort StudiesColombiaHumansProbabilityReoperationRetrospective Studies

Identifiers

PMID37624801
PMCPMC10456128
OpenAlexW4386158444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.