Evidence map›Paper›PMID 37624587›Full record

ReviewEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2023

Transcatheter interventions for left-sided valvular heart disease complicated by cardiogenic shock: a consensus statement from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) in collaboration with the Association for Acute Cardiovascular Care (ACVC) and the ESC Working Group on Cardiovascular Surgery.

Chiara Fraccaro, Nicole Karam, Helge Möllmann, Sabine Bleiziffer, Nikolaos Bonaros, Rui Campante Teles, Pedro Carrilho Ferreira, Alaide Chieffo, Martin Czerny, Erwan Donal and 16 more

Registry-linked trialOpen access · greenAbstract readReviewConsensus Statement
In one paragraph

Review in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07309029 (PROspective Evaluation of Pre-empTive Left Atrial Venoarterial Extra-Corporeal Membrane oxygenaTion for Complex High-risk Transcatheter Aortic Valve Replacement), which is not on this map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07309029 recruitingnot on this mapstarted 2026, after this paper: background citation

PROspective Evaluation of Pre-empTive Left Atrial Venoarterial Extra-Corporeal Membrane oxygenaTion for Complex High-risk Transcatheter Aortic Valve Replacement: PROTECT-TAVR

Typeobservational_patient_registrySponsorAtlantic Health SystemRan2026 to 2027Enrolled30ConditionsSevere Aortic Stenosis, Cardiogenic Shock, Cardiogenic Shock, ECMO, Trans-catheter Aortic Valve ImplantationArmsLeft Atrial Veno-Arterial Extracorporeal Membrane Oxygenation (LAVA-ECMO)
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Direct Comparison of Urgent Transcatheter Aortic Valve Implantation and Balloon Aortic Valvuloplasty: A Systematic Review and Meta-Analysis.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Pooled it
  2. SCAI/EAPCI/ACVC Expert Consensus Statement on Cardiogenic Shock in Women.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Guideline
  3. Pooled it
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Left Atrial Veno-Arterial Extracorporeal Membrane Oxygenation In Valvular Cardiogenic Shock.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. [The Hospitalized Patient with Severe Aortic Stenosis].Archivos peruanos de cardiologia y cirugia cardiovascular
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 19 institutions in 8 countries.

Chiara FraccaroDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Nicole KaramHeart Valves Unit, Georges Pompidou European Hospital, Université Paris Cité, INSERM, Paris, France.
Helge MöllmannDepartment of Cardiology, St. Johannes Hospital, Dortmund, Germany.
Sabine BleizifferHeart and Diabetes Center NRW, Bad Oeynhausen, Germany.
Nikolaos BonarosCardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Rui Campante TelesHospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental (HSC), Carnaxide, Portugal and Comprehensive Health Research Center (CHRC), Nova Medical School, Lisbon, Portugal.
Pedro Carrilho FerreiraCardiology Department, Santa Maria University Hospital, CHULN, CAML, CCUL, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.
Alaide ChieffoInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Martin CzernyDepartment of Cardiovascular Surgery, University Heart Centre, Freiburg University, Freiburg, Germany.
Erwan DonalService de Cardiologie, CCP CHU de Rennes, University of Rennes, INSERM, LTSI-UMR 1099, Rennes, France.
Dariusz DudekInstitute of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
Nicolas DumonteilClinique Pasteur, Toulouse, France.
Giovanni EspositoDivisions of Cardiology and Cardiothoracic Surgery, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy.
Stephane FournierService of Cardiology, Lausanne University Hospital, Lausanne, Switzerland and University of Lausanne, Lausanne, Switzerland.
Christian HassagerDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Won-Keun KimDepartment of Cardiology, St. Johannes Hospital, Dortmund, Germany.
Konstantin A KrychtiukDuke Clinical Research Institute, Durham, NC, USA.
Julinda MehilliDepartment of Cardiology, German Centre for Cardiovascular Research (DZHK), Ludwig Maximilian University of Munich, Partner Site Munich Heart Alliance, Munich, Germany.
Jerzy PręgowskiDepartment of Interventional Cardiology and Angiology, National Institute of Cardiology, Warszawa, Poland.
Giulio G StefaniniDepartment of Biomedical Sciences Humanitas University, Pieve Emanuele, Italy.
Julien TernacleInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec, QC, Canada and Université Laval, Quebec, QC, Canada.
Holger ThieleDepartment of Internal Medicine/Cardiology, Heart Center Leipzig, Leipzig, Germany and University of Leipzig, Leipzig, Germany.
Matthias ThielmannDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, Essen, Germany.
Flavien VincentService de Cardiologie, Centre Hospitalier Universitaire de Lille, Lille, France.
Ralph Stephan von BardelebenHeart Valve Center, Heart and Vascular Center, Universitätsmedizin Mainz, Mainz, Germany.
Giuseppe TarantiniDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
St.-Johannes-Hospital Dortmund · DEUniversity of Padua · ITCentre Hospitalier Universitaire de Lille · FRClinique Pasteur · FRFederico II University Hospital · ITHeart and Diabetes Center North Rhine-Westphalia · DEHôpital Cardiologique du Haut-Lévêque · FRHumanitas University · ITInstitute of Cardiology · PLJagiellonian University · PLJohannes Gutenberg University Mainz · DEMedical University of Vienna · ATRigshospitalet · DKSan Raffaele University of Rome · ITUniversität Innsbruck · ATUniversity of Applied Sciences Landshut · DEUniversity of Freiburg · DEUniversity of Lisbon · PTWest German Heart and Vascular Center Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Valvular heart disease (VHD) is one of the most frequent causes of heart failure (HF) and is associated with poor prognosis, particularly among patients with conservative management. The development and improvement of catheter-based VHD interventions have broadened the indications for transcatheter valve interventions from inoperable/high-risk patients to younger/lower-risk patients. Cardiogenic shock (CS) associated with severe VHD is a clinical condition with a very high risk of mortality for which surgical treatment is often deemed a prohibitive risk. Transcatheter valve interventions might be a promising alternative in this setting given that they are less invasive. However, supportive scientific evidence is scarce and often limited to small case series. Current guidelines on VHD do not contain specific recommendations on how to manage patients with both VHD and CS. The purpose of this clinical consensus statement, developed by a group of international experts invited by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) Scientific Documents and Initiatives Committee, is to perform a review of the available scientific evidence on the management of CS associated with left-sided VHD and to provide a rationale and practical approach for the application of transcatheter valve interventions in this specific clinical setting.

Indexed as

Heart Valve DiseasesShock, CardiogenicCardiac CatheterizationEuropeHeart Valve Prosthesis ImplantationHumansTranscatheter Aortic Valve ReplacementTreatment Outcome

Identifiers

PMID37624587
PMCPMC10587846
OpenAlexW4386152499

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.