Evidence map›Paper›PMID 37624485›Full record

ArticleCell and tissue banking2024

Preanalytical variables influencing the interpretation and reporting of biological tests on blood samples of living and deceased donors for human body materials.

Elizaveta Padalko, Luc Colenbie, Alain Delforge, Nadine Ectors, Johan Guns, Romain Imbert, Hilde Jansens, Jean-Paul Pirnay, Marie-Pierre Rodenbach, Ivan Van Riet and 4 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell and tissue banking, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Elizaveta PadalkoDepartment of Medical Microbiology, Ghent University Hospital, C. Heymanslaan 10, 9000, Ghent, Belgium. elizaveta.padalko@uzgent.be.ORCID http://orcid.org/0000-0002-8101-6957
Luc ColenbieWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Alain DelforgeWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Nadine EctorsWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Johan GunsWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Romain ImbertWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Hilde JansensWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Jean-Paul PirnayWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Marie-Pierre RodenbachWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Ivan Van RietWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Anne VansteenbruggeWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Gilbert VerbekenWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Muriel BaltesWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Hilde BeeleWorking Group on Cells, Tissues and Organs of the Superior Health Council, Brussels, Belgium.
Ghent University Hospital · BEMédecins du Monde · BEQueen Astrid Military Hospital · BEAntwerp University Hospital · BECatholic University of America · USFond du Lac Reservation · USInstitut Jules Bordet · BEVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the present paper, the Working Group on Cells, Tissues and Organs and other experts of the Superior Health Council of Belgium aimed to provide stakeholders in material of human origin with advice on critical aspects of serological and nucleic acid test (NAT) testing, to improve virological safety of cell- and tissue and organ donation. The current paper focusses on a number of preanalytical variables which can be critical for any medical biology examination: (1) sampling related variables (type of samples, collection of the samples, volume of the sample, choice of specific tubes, identification of tubes), (2) variables related to transport, storage and processing of blood samples (transport, centrifugation and haemolysis, storage before and after centrifugation, use of serum versus plasma), (3) variables related to dilution (haemodilution, pooling of samples), and (4) test dependent variables (available tests and validation). Depending on the type of donor (deceased donor (heart-beating or non-heart beating) versus living donor (allogeneic, related, autologous), and the type of donated human material (cells, tissue or organs) additional factors can play a role: pre- and post-mortem sampling, conditions of sampling (e.g. morgue), haemodilution, possibility of retesting.

Indexed as

Tissue DonorsBlood Specimen CollectionHuman BodyHumansLiving DonorsPre-Analytical PhaseSpecimen HandlingTissue and Organ ProcurementBiological testDeceasedDonor of human body materialLivingPost-mortemPreanalytical variables

Identifiers

PMID37624485
PMCPMC11143040
OpenAlexW4386153417

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.