Evidence map›Paper›PMID 37624415›Full record

ArticleEuropean radiology2023

Prediction of postoperative recurrence in resectable pancreatic body/tail adenocarcinoma: a novel risk stratification approach using a CT-based nomogram.

Tiansong Xie, Xuebin Xie, Wei Liu, Lei Chen, Kefu Liu, Zhengrong Zhou

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Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Tiansong XieDepartment of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China.
Xuebin XieMedical Imaging Center, Kiang Wu Hospital, Macau, China.
Wei LiuDepartment of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China.
Lei ChenDepartment of Radiology, Fudan University Shanghai Cancer Center (Minhang Campus), Shanghai, China.
Kefu LiuDepartment of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu, China. lkf77@126.com.
Zhengrong ZhouDepartment of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China. zhouzr-16@163.com.ORCID http://orcid.org/0000-0002-9922-1000
Shanghai Medical College of Fudan University · CNFudan University Shanghai Cancer Center · CNKiang Wu Hospital · CNSuzhou Municipal Hospital · CN

Funding

Shanghai Association for Science and Technology 22490760800Suzhou Municipal Health Commission GSWS2019020
6 · The paper itself

Abstract

objectivesTo identify prognostic CT features that predict recurrence in patients with resectable pancreatic body/tail adenocarcinoma (PBTA) and construct a CT-based nomogram for preoperative risk stratification.

methodsA total of 258 patients with resectable PBTA who underwent upfront surgery were retrospectively enrolled (development cohort, n = 172; validation cohort, n = 86), and their clinical and CT features were analyzed. Stepwise Cox proportional hazard analysis was performed to identify prognostic features and construct a predictive nomogram for recurrence-free survival (RFS). The prognostic performance of the CT-based nomogram was validated and compared to the 8

resultsIn the development cohort, the following five CT features for predicting recurrence were identified to construct the nomogram: tumor density in the venous phase, tumor necrosis, adjacent organ invasion, splenic vein invasion, and superior mesenteric vein/portal vein abutment. In the validation cohort, the CT-based nomogram showed a concordance index of 0.65 (95% confidence interval: 0.58-0.73), which was higher than the 8

conclusionsThe proposed nomogram provided accurate recurrence risk stratification for patients with resectable PBTA in a preoperative setting and may be used to facilitate clinical decision-making. CLINICAL RELEVANCE STATEMENT: The proposed CT-based nomogram, based on easily available CT features, may serve as an effective and convenient tool for stratifying further the recurrence risk of patients with pancreatic body/tail adenocarcinoma. KEY POINTS: • The CT-based nomogram, incorporating five commonly used CT features, successfully preoperatively stratified patients with resectable PBTA into distinct prognosis groups. • Tumor density in the venous phase, tumor necrosis, splenic vein invasion, adjacent organ invasion, and superior mesenteric vein/portal vein abutment were associated with RFS in patients with resectable PBTA. • The CT-based nomogram exhibited better predictive performance for recurrence than the 8

Indexed as

AdenocarcinomaNomogramsHumansNecrosisOrganophosphorus CompoundsPancreatic NeoplasmsPortal VeinPrognosisRetrospective StudiesRisk AssessmentTomography, X-Ray Computed2-phosphonobutane-1,2,4-tricarboxylic acidOrganophosphorus CompoundsCarcinomaNomogramPancreatic neoplasmsRecurrenceX-ray computed tomography

Identifiers

PMID37624415
OpenAlexW4386153595

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.