Evidence map›Paper›PMID 37624413›Full record

ArticleEuropean radiology2024

Stent-specific fat attenuation index is associated with target vessel revascularization after PCI.

Feng Xu, Chengcheng Wang, Qing Tao, Jian Zhang, Mingming Zhao, Shiwei Shi, Mengmeng Zhu, Chunxiang Tang, Longjiang Zhang, Changsheng Zhou and 1 more

Abstract read
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In one paragraph

Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Feng Xu *Department of Radiology, the First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Chengcheng Wang *Department of Medical Imaging, the Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, 223800, Jiangsu, China.
Qing TaoDepartment of Radiology, the First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Jian ZhangDepartment of Medical Imaging, the Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, 223800, Jiangsu, China.
Mingming ZhaoDepartment of Medical Imaging, the Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, 223800, Jiangsu, China.
Shiwei ShiDepartment of Medical Imaging, the Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, 223800, Jiangsu, China.
Mengmeng ZhuDepartment of Medical Imaging, the Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, 223800, Jiangsu, China.
Chunxiang TangDepartment of Radiology, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, Jiangsu, China.
Longjiang ZhangDepartment of Radiology, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, Jiangsu, China.
Changsheng ZhouDepartment of Radiology, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, Jiangsu, China. njzhouyisheng@qq.com.
Chunhong HuDepartment of Radiology, the First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China. hch5305@163.com.ORCID http://orcid.org/0000-0003-1292-9370
Nanjing Medical University · CNNanjing General Hospital of Nanjing Military Command · CNSoochow University · CN

Funding

"333 Project" of Jiangsu Province BRA2018264Gusu health talent project of Suzhou GSWS2020003Suqian Science and Technology Support Program S201626
6 · The paper itself

Abstract

objectivesTo explore the clinical relevance of stent-specific perivascular fat attenuation index (FAI) in patients with stent implantation.

methodsA total of 162 consecutive patients who underwent coronary computed tomography angiography (CCTA) following stent implantation were retrospectively included. The stent-specific FAI at 2 cm adjacent to the stent edge was calculated. The endpoints were defined as target vessel revascularization (TVR) on the stented vessel after CCTA and readmission times due to chest pain after stent implantation. Binary logistic regression analysis for TVR and ordinal regression models were conducted to identify readmission times (0, 1, and ≥ 2) with generalized estimating equations on a per-stent basis.

resultsOn a per-stent basis, 9 stents (4.5%) experienced TVR after PCI at a median 30 months' follow-up duration. Stent-specific FAI differed significantly among subgroups of patients with stent implantation and different readmission times (p = 0.002); patients with at least one readmission had higher stent-specific FAI than those without readmission (p < 0.001). Bifurcated stents (odds ratio [OR]: 11.192, p = 0.001) and stent-specific FAI (OR: 1.189, p = 0.04) were independently associated with TVR. With no readmission as a reference, stent-specific FAI (OR: 0.984, p = 0.007) was an independent predictor for hospital readmission times ≥ 2 (p = 0.003).

conclusionNon-invasive stent-specific FAI derived from CCTA was found to be associated with TVR, which was a promising imaging marker for functional assessment in patients who underwent stent implantation. CLINICAL RELEVANCE STATEMENT: Noninvasive fat attenuation index adjacent to the stents edge derived from CCTA, an imaging marker reflecting the presence of inflammation acting on the neointimal tissue at the sites of coronary stenting, might be relevant clinically with target vessel revascularization. KEY POINTS: • Non-invasive stent-specific FAI derived from CCTA was associated with TVR (OR: 1.189 [95% CI: 1.007-1.043], p = 0.04) in patients who underwent stent implantation. • Stent-specific FAI significantly differed among a subgroup of patients with chest pain after stent implantation and with different readmission times (p = 0.002); the patients with at least one readmission had higher stent-specific FAI than those without readmission (p < 0.001). • Non-invasive stent-specific FAI derived from CCTA could be used as an imaging maker for the functional assessment of patients following stent implantation.

Indexed as

Coronary Artery DiseasePercutaneous Coronary InterventionChest PainCoronary AngiographyHumansRetrospective StudiesStentsTreatment OutcomeAdipose tissueComputed tomography angiographyCoronary restenosisMyocardial revascularization

Identifiers

PMID37624413
OpenAlexW4386152666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.