Evidence map›Paper›PMID 37624349›Full record

ArticleTropical medicine and infectious disease2023

The Cost-Effectiveness of the BEAT-TB Regimen for Pre-Extensively Drug-Resistant TB.

Malaisamy Muniyandi, Paranchi Murugesan Ramesh, William A Wells, Umesh Alavadi, Suvanand Sahu, Chandrasekaran Padmapriyadarsini

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Tuberculosis: An Update for the Clinician.Respirology (Carlton, Vic.) · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Malaisamy MuniyandiICMR-National Institute for Research in Tuberculosis, Chennai 600031, India.ORCID 0000-0002-1209-4062
Paranchi Murugesan RameshGovernment Ottery TB Hospital, Ottery, Chennai 600012, India.
William A WellsUnited States Agency for International Development (USAID), Washington, DC 20004, USA.ORCID 0000-0003-4360-1263
Umesh AlavadiUnited States Agency for International Development (USAID), Chanakyapuri, New Delhi, Delhi 110021, India.
Suvanand SahuStop TB Partnership Secretariat, 1218 Geneva, Switzerland.
Chandrasekaran PadmapriyadarsiniICMR-National Institute for Research in Tuberculosis, Chennai 600031, India.ORCID 0000-0002-1324-4595
National Institute of Research in Tuberculosis · INUnited States Agency for International Development · US

Funding

USAID 5122019
6 · The paper itself

Abstract

objectiveTo measure the economic impacts of the longer pre-XDR-TB treatment regimen and the shorter BEAT-TB India regimen.

methodsIn the current study, the economic impacts of the current 18-month pre-XDR-TB treatment regimen and the 6-9 month BEAT-TB regimen were evaluated using an economic model via a decision tree analysis from a societal perspective. The incremental costs and quality-adjusted life years (QALYs) gained from the introduction of the BEAT-TB regimen for pre-XDR-TB patients were estimated.

resultsFor a cohort of 1000 pre-XDR-TB patients, we found that the BEAT-TB India regimen yielded higher undiscounted life years (40,548 vs. 21,009) and more QALYs gained (27,633 vs. 15,812) than the 18-month regimen. The BEAT-TB India regimen was found to be cost-saving, with an incremental cost of USD -128,651 when compared to the 18-month regimen. The current analysis did not consider the possibility of reduced TB recurrence after use of the BEAT-TB regimen, so it might have under-estimated the benefits.

conclusionAs a lower-cost intervention with improved health outcomes, the BEAT-TB India regimen is dominant when compared to the 18-month regimen.

Indexed as

cost-effective BEAT-TB regimeneconomic impactinfectious diseasespre-XDR-TB treatment regimenshorter BEAT-TB India regimensocietal perspectivetuberculosis

Identifiers

PMID37624349
PMCPMC10459879
OpenAlexW4385761333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.