Evidence map›Paper›PMID 37624331›Full record

ArticleTropical medicine and infectious disease2023

The Trend, Characteristics and Treatment Outcomes in Patients with Tuberculosis Undergoing Thoracic Surgery in the Kyrgyz Republic between 2017 and 2021.

Konushbek Sakmamatov, Yulia Kuznetsova, Kylychbek Istamov, Daniil Shauer, Jaya Prasad Tripathy, Anthony D Harries, Kudaibergen Osmonaliev, Olga Goncharova

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In one paragraph

Article in Tropical medicine and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Konushbek SakmamatovFaculty of Medicine, Ala-Too International University, Bishkek 720000, Kyrgyzstan.
Yulia KuznetsovaInternational Charitable Foundation "Alliance for Public Health", 01601 Kiev, Ukraine.ORCID 0000-0002-8743-1764
Kylychbek IstamovSchool of Medicine, Osh State University, Osh 723500, Kyrgyzstan.
Daniil ShauerNational Centre of Phthisiology, Ministry of Health, Bishkek 720000, Kyrgyzstan.
Jaya Prasad TripathyDepartment of Community Medicine, All India Institute of Medical Sciences, Nagpur 441108, India.
Anthony D HarriesInternational Union Against Tuberculosis and Lung Disease, 2 Rue Jean Lantier, 75001 Paris, France.ORCID 0000-0001-6113-9741
Kudaibergen OsmonalievFaculty of Medicine, Ala-Too International University, Bishkek 720000, Kyrgyzstan.
Olga GoncharovaNational Centre of Phthisiology, Ministry of Health, Bishkek 720000, Kyrgyzstan.
Ala-Too International University · KGMinistry of Health of Kyrgyzstan · KGAlliance for Public Health · UAAll India Institute of Medical Sciences, Nagpur · INOsh State University · KGUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgery has played an important role in managing complicated tuberculosis in former Soviet Union countries, including the Kyrgyz Republic. However, published information is limited. This study aimed to document the trend, characteristics and outcomes of tuberculosis patients who underwent thoracic surgery, using routinely collected data. Between 2017 and 2021, 4-7% of tuberculosis patients in the Kyrgyz Republic underwent thoracic surgery in two centres in Bishkek and Osh. In 2021, case records were retrieved in 264 (78%) of 340 patients undergoing thoracic surgery in the country. The most common indications for surgery were pleural exudate/empyema in 127 (44%) and tuberculoma in 83 (32%). Most patients (73%) underwent surgery within 30 days of starting TB treatment. Two-thirds of patients underwent radical surgery, and surgical outcomes were excellent in 99% of patients with one death. Post-operatively, 63 (23%) patients had no TB detected by the histology, with the two most common specified conditions being lung cancer and pulmonary hydatid disease. TB treatment was stopped in these patients. Of the 201 patients with confirmed TB after surgery, TB-treatment success was documented in 163 (81%), died/failure/lost to follow-up in 10 (5%) and not evaluated in 28 (14%). This study shows that thoracic surgery is feasible, safe and effective in the routine programme setting. Recommendations are made to strengthen referral and monitoring systems.

Indexed as

drug-resistant tuberculosisKyrgyzstanoperational researchpleural empyemaSORT ITsurgical treatment outcomesTB treatment outcomesthoracic surgerytuberculomatuberculosis

Identifiers

PMID37624331
PMCPMC10458206
OpenAlexW4385462732

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.