Evidence map›Paper›PMID 37624258›Full record

ArticleToxins2023

Okadaic Acid Detection through a Rapid and Sensitive Amplified Luminescent Proximity Homogeneous Assay.

Yuan Qin, Jiayu Li, Jiani Kuang, Sicheng Shen, Xiumei Zhou, Xueqin Zhao, Biao Huang, Bingnan Han

Abstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuan QinCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.ORCID 0000-0002-5651-8293
Jiayu LiCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Jiani KuangCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Sicheng ShenCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Xiumei ZhouCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Xueqin ZhaoCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.ORCID 0000-0002-4214-6599
Biao HuangCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Bingnan HanCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.ORCID 0000-0003-3616-9409

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Okadaic acid (OA), a marine biotoxin produced by microalgae, poses a significant threat to mariculture, seafood safety, and human health. The establishment of a novel, highly sensitive detection method for OA would have significant practical and scientific implications. Therefore, the purpose of this study was to develop an innovative approach for OA detection. A competitive amplified luminescent proximity homogeneous assay (AlphaLISA) was developed using the principle of specific antigen-antibody binding based on the energy transfer between chemiluminescent microspheres. The method was non-washable, sensitive, and rapid, which could detect 2 × 10

Indexed as

Biological AssayMicroalgaeChromatography, High Pressure LiquidHumansLuminescent MeasurementsOkadaic AcidOkadaic Acidamplified luminescent proximity homogeneous assaydiarrheic shellfish poisoningimmunoassayokadaic acidshellfish

Identifiers

PMID37624258
PMCPMC10467062

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.