Evidence map›Paper›PMID 37624158›Full record

ArticleToxics2023

Causes of Death during the Intravenous Infusion of Dimethylsulphoxide and Hydrogen Peroxide in the Course of Alternative Medicine Therapy.

Szymon Rzepczyk, Paweł Świderski, Karina Sommerfeld-Klatta, Artur Tezyk, Magdalena Łukasik-Głębocka, Barbara Zielińska-Psuja, Zbigniew Żaba, Czesław Żaba

Open access · goldAbstract readCase Reports
In one paragraph

Article in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Szymon RzepczykDepartment of Forensic Medicine, Poznan University of Medical Sciences, Rokietnicka 10, 60-806 Poznan, Poland.ORCID 0000-0001-6330-1511
Paweł ŚwiderskiDepartment of Forensic Medicine, Poznan University of Medical Sciences, Rokietnicka 10, 60-806 Poznan, Poland.
Karina Sommerfeld-KlattaDepartment of Toxicology, Poznan University of Medical Sciences, Dojazd 30, 60-631 Poznan, Poland.
Artur TezykDepartment of Forensic Medicine, Poznan University of Medical Sciences, Rokietnicka 10, 60-806 Poznan, Poland.
Magdalena Łukasik-GłębockaDepartment of Emergency Medicine, Poznan University of Medical Sciences, Rokietnicka 7, 60-806 Poznan, Poland.ORCID 0000-0003-0538-873X
Barbara Zielińska-PsujaDepartment of Toxicology, Poznan University of Medical Sciences, Dojazd 30, 60-631 Poznan, Poland.
Zbigniew ŻabaDepartment of Emergency Medicine, Poznan University of Medical Sciences, Rokietnicka 7, 60-806 Poznan, Poland.
Czesław ŻabaDepartment of Forensic Medicine, Poznan University of Medical Sciences, Rokietnicka 10, 60-806 Poznan, Poland.
Poznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unconventional (alternative, natural) medicine in Poland and worldwide includes hundreds of non-scientifically verified "treatment" modalities. Among the most popular are biological therapies using chemical or natural compounds administered with injection or drip infusion. The latter has found the most excellent use in treating rheumatological and dermatological diseases and certain types of cancer. Vitamin infusions, curcumin, glutathione, perhydrol and dimethylsulphoxide (DMSO) have gained popularity among clients of natural medicine clinics. The present study aims to analyse the case of a 37-year-old woman who was administered infusions containing perhydrol and DMSO (0.5 mL 0.04% hydrogen peroxide/0.5 mL p.d.a DMSO in saline) due to a MTHFR A1298C mutation. After having the next infusion, the woman complained of nausea and then became unconscious. Subsequently, she suffered respiratory and cardiac arrest. Adequate resuscitation was undertaken. After being taken to the hospital, the patient was in critical condition and died due to increasing multiple-organ failure. Initially, there was suspected DMSO poisoning as it was the only compound to have been administered as an intravenous infusion. However, it was not until the analysis of the secured evidence that it became clear that the patient had also been given an intravenous solution of hydrogen peroxide, H

Indexed as

alternative medicineDMSOhydrogen peroxideintoxicationmedication error

Identifiers

PMID37624158
PMCPMC10457729
OpenAlexW4385344789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.