Evidence map›Paper›PMID 37623921›Full record

ArticleMethods and protocols2023

Application of a Customised Franz-Type Cell Coupled with HPTLC to Monitor the Timed Release of Bioactive Components in Complex Honey Matrices.

Md Lokman Hossain, Minh Nguyen, Leah Benington, Lee Yong Lim, Katherine Hammer, Dhanushka Hettiarachchi, Cornelia Locher

Abstract read
In one paragraph

Article in Methods and protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Md Lokman HossainDivision of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.ORCID 0000-0001-6339-2767
Minh NguyenDivision of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.
Leah BeningtonDivision of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.ORCID 0000-0002-2459-315X
Lee Yong LimDivision of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.ORCID 0000-0002-7307-0742
Katherine HammerSchool of Biomedical Sciences, University of Western Australia, Crawley 6009, Australia.
Dhanushka HettiarachchiDivision of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.
Cornelia LocherDivision of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia.ORCID 0000-0001-8773-3036

Funding

University of Western Australia University Postgraduate Award (UPA)
6 · The paper itself

Abstract

The aim of this study was to assess the release profile of components in five different honeys (a New Zealand Manuka and two Western Australian honeys, a Jarrah honey and a Coastal Peppermint honey) and their corresponding honey-loaded gel formulations using a custom-designed Franz-type diffusion cell in combination with High-Performance Thin-Layer Chromatography (HPTLC). To validate the suitability of the customised setup, release data using this new approach were compared with data obtained using a commercial Franz cell apparatus, which is an established analytical tool to monitor the release of active ingredients from topical semisolid products. The release profiles of active compounds from pure honey and honey-loaded formulations were found to be comparable in both types of Franz cells. For example, when released either from pure honey or its corresponding pre-gel formulation, the percentage release of two Jarrah honey constituents, represented by distinct bands at R

Indexed as

custom-designed Franz-type diffusion celldialysis membraneFranz cellhoneyHPTLCin vitro dissolutionrelease profiletopical honey-loaded products

Identifiers

PMID37623921
PMCPMC10459218

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.