ReviewMarine drugs2023
Overview and Challenges of Large-Scale Cultivation of Photosynthetic Microalgae and Cyanobacteria.
Review in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed.
- Engineering cyanobacterial resilience for cadmium bioremediation: linking Cd speciation, cellular detoxification, and synthetic biology.RSC advances · 2026Review
- Process intensification for the protein production from microalgae: a comprehensive review.Bioresources and bioprocessing · 2026Review
- Precision Microalgae: A New Conceptual Framework for Bioengineering Applications.Bioengineering (Basel, Switzerland) · 2026Review
- Integration of domestic wastewater and native Tetradesmus obliquus for bioremediation and production of biomass rich in protein and polyunsaturated fatty acids.Environmental science and pollution research international · 2026Article
- Optimization of cultivation mode for pilot-scale biomass and B-phycoerythrin production by red microalgae Porphyridium purpureum in different seasons.Folia microbiologica · 2026Article
- Advancing microalgae biomass cultivation for an integrated sustainable wastewater treatment and resource recovery.iScience · 2026Review
- From contamination to valorisation: a case study assessing culture contamination effect on the biofuel potential and nanomechanical properties of Parachlorella kessleri.Biotechnology for biofuels and bioproducts · 2026Article
- Next-Generation Cyanobacterial Biocontrol Agents for Crop Fungal Diseases: Molecular Mechanisms, Omics Insights, Applications, and Biosafety Considerations.Journal of basic microbiology · 2026Review
- Food for thought : The role of life cycle thinking in sustainable food system transitions.EMBO reports · 2026Article
- Cyanobacteria as a Photosynthetic Chassis for Metabolic Pathway Engineering with Heterologous Gene Expression.Current issues in molecular biology · 2026Review
- Red Light Enhances Biomass and Bioactive Compounds Through Photosynthetic Acclimation inMarine drugs · 2026Article
- Engineering primary metabolism for sustainable production of isoprene in Synechocystis sp. PCC 6803.Microbial cell factories · 2026Article
- Roadmap for light interaction with biophotonic surfaces and their diverse applications.Journal of biomedical optics · 2026Article
- Mitigation of microbial biocontamination in cyanobacterial ethanol synthesis via alginate encapsulation.Bioresources and bioprocessing · 2026Article
- Fascinating single-cell red algae: models for evolution and adaptation.The New phytologist · 2026Review
- Microalgae-Driven Circular Agriculture: System Integration, Nutrient Recovery, and AI-Assisted Optimization.Microorganisms · 2026Review
- Exploring Microalgae as a Novel Resource for Hepatocellular Carcinoma Therapy.Molecules (Basel, Switzerland) · 2026Review
- Effects of Different Culture Conditions on the Synthesis and Distribution of Polyunsaturated Fatty Acids (EPA and ARA) inMarine drugs · 2026Article
- Artificial intelligence tools for AgNP-SSB-SN and AgNP-CSS-SN biosynthesis from Synechococcus PCC 11901 and Chlorella sorokiniana MSP1 for hazardous dyes remediation.Scientific reports · 2026Article
- Analytical Framework to Navigate Microalgae-Based Product Development-Aligning Commercialization and Regulatory Pathways.Marine drugs · 2026Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microalgae and cyanobacteria are diverse groups of organisms with great potential to benefit societies across the world. These organisms are currently used in food, feed, pharmaceutical and cosmetic industries. In addition, a variety of novel compounds are being isolated. Commercial production of photosynthetic microalgae and cyanobacteria requires cultivation on a large scale with high throughput. However, scaling up production from lab-based systems to large-scale systems is a complex and potentially costly endeavor. In this review, we summarise all aspects of large-scale cultivation, including aims of cultivation, species selection, types of cultivation (ponds, photobioreactors, and biofilms), water and nutrient sources, temperature, light and mixing, monitoring, contamination, harvesting strategies, and potential environmental risks. Importantly, we also present practical recommendations and discuss challenges of profitable large-scale systems associated with economical design, effective operation and maintenance, automation, and shortage of experienced phycologists.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.