Evidence map›Paper›PMID 37623720›Full record

ReviewMarine drugs2023

Review of Marine Cyanobacteria and the Aspects Related to Their Roles: Chemical, Biological Properties, Nitrogen Fixation and Climate Change.

Hesham R El-Seedi, Mohamed F El-Mallah, Nermeen Yosri, Muaaz Alajlani, Chao Zhao, Muhammad A Mehmood, Ming Du, Hammad Ullah, Maria Daglia, Zhiming Guo and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Pathogenic effects ofApplied and environmental microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Adaptive Evolution Signatures inMicroorganisms · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 7 countries.

Hesham R El-SeediInternational Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China.
Mohamed F El-MallahDepartment of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt.
Nermeen YosriChemistry Department of Medicinal and Aromatic Plants, Research Institute of Medicinal and Aromatic Plants (RIMAP), Beni-Suef University, Beni-Suef 62514, Egypt.
Muaaz AlajlaniFaculty of Pharmacy, Al-Sham Private University, Damascus 0100, Syria.ORCID 0000-0001-9087-6863
Chao ZhaoCollege of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0003-1096-632X
Muhammad A MehmoodBioenergy Research Center, Department of Bioinformatics and Biotechnology, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Ming DuSchool of Food Science and Technology, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, China.
Hammad UllahDepartment of Pharmacy, University of Napoli Federico II, Via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0001-9437-676X
Maria DagliaInternational Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-4870-7713
Zhiming GuoChina Light Industry Key Laboratory of Food Intelligent Detection & Processing, School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0001-6416-7457
Shaden A M KhalifaInternational Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China.
Qiyang ShouSecond Clinical Medical College, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Jiangsu University · CNBeni-Suef University · EGDalian Polytechnic University · CNFujian Agriculture and Forestry University · CNGovernment College University, Faisalabad · PKMenoufia University · EGSyrian Private University · SYUniversity of Naples Federico II · ITZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine cyanobacteria are an ancient group of photosynthetic microbes dating back to 3.5 million years ago. They are prolific producers of bioactive secondary metabolites. Over millions of years, natural selection has optimized their metabolites to possess activities impacting various biological targets. This paper discusses the historical and existential records of cyanobacteria, and their role in understanding the evolution of marine cyanobacteria through the ages. Recent advancements have focused on isolating and screening bioactive compounds and their respective medicinal properties, and we also discuss chemical property space and clinical trials, where compounds with potential pharmacological effects, such as cytotoxicity, anticancer, and antiparasitic properties, are highlighted. The data have shown that about 43% of the compounds investigated have cytotoxic effects, and around 8% have anti-trypanosome activity. We discussed the role of different marine cyanobacteria groups in fixing nitrogen percentages on Earth and their outcomes in fish productivity by entering food webs and enhancing productivity in different agricultural and ecological fields. The role of marine cyanobacteria in the carbon cycle and their outcomes in improving the efficiency of photosynthetic CO

Indexed as

Climate ChangeCyanobacteriaAgricultureAnimalsCarbon DioxideNitrogen FixationCarbon Dioxideclimate changeclinical trialshistorical recordmarine cyanobacterianitrogen fixationsecondary metabolites

Identifiers

PMID37623720
PMCPMC10456358
OpenAlexW4385543961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.