Evidence map›Paper›PMID 37623706›Full record

ArticleMarine drugs2023

Investigating A Multi-Domain Polyketide Synthase in

Saddef Haq, Benjamin L Oyler, Ernest Williams, Mohd M Khan, David R Goodlett, Tsvetan Bachvaroff, Allen R Place

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Bioactive Polyketides fromMarine drugs · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Saddef HaqInstitute for Marine and Environmental Technologies, University of Maryland Center for Environmental Science, 701 East Pratt St., Baltimore, MD 21202, USA.
Benjamin L OylerUniversity of Maryland School of Medicine, 655 W. Baltimore Street, Baltimore, MD 21201, USA.ORCID 0000-0003-3436-9175
Ernest WilliamsInstitute for Marine and Environmental Technologies, University of Maryland Center for Environmental Science, 701 East Pratt St., Baltimore, MD 21202, USA.
Mohd M KhanUniversity of Maryland School of Medicine, 655 W. Baltimore Street, Baltimore, MD 21201, USA.ORCID 0000-0003-2793-1705
David R GoodlettDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC V8S 1P7, Canada.ORCID 0000-0002-8045-8200
Tsvetan BachvaroffInstitute for Marine and Environmental Technologies, University of Maryland Center for Environmental Science, 701 East Pratt St., Baltimore, MD 21202, USA.
Allen R PlaceInstitute for Marine and Environmental Technologies, University of Maryland Center for Environmental Science, 701 East Pratt St., Baltimore, MD 21202, USA.ORCID 0000-0003-4692-2388
University of Maryland, Baltimore · USUniversity of Victoria · CA

Funding

NIH HHS R01ES021949-01/NSF OCE1313888
6 · The paper itself

Abstract

Dinoflagellates are unicellular organisms that are implicated in harmful algal blooms (HABs) caused by potent toxins that are produced through polyketide synthase (PKS) pathways. However, the exact mechanisms of toxin synthesis are unknown due to a lack of genomic segregation of fat, toxins, and other PKS-based pathways. To better understand the underlying mechanisms, the actions and expression of the PKS proteins were investigated using the toxic dinoflagellate

Indexed as

CeruleninDinoflagellidaBlotting, WesternHarmful Algal BloomPolyketide SynthasesCeruleninPolyketide SynthasescerulenindinoflagellatePKStoxin

Identifiers

PMID37623706
PMCPMC10455422
OpenAlexW4385347433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.