Evidence map›Paper›PMID 37623703›Full record

ArticleMarine drugs2023

Generation of Bioactive Peptides from

Maria Hayes, Rotimi E Aluko, Elena Aurino, Leticia Mora

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 4 countries.

Maria HayesDepartment of Food BioSciences, Teagasc Food Research Centre, Ashtown, D15 DY05 Dublin, Ireland.
Rotimi E AlukoDepartment of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0002-9025-2513
Elena AurinoDepartment of Food BioSciences, Teagasc Food Research Centre, Ashtown, D15 DY05 Dublin, Ireland.
Leticia MoraInstituto de Agroquímica y Tecnología de Alimentos (CSIC), Avenue Agustín Escardino 7, Valencia, 46980 Paterna, Spain.ORCID 0000-0003-1571-5781
Teagasc - The Irish Agriculture and Food Development Authority · IEInstituto de Agroquímica y Tecnología de Alimentos · ESUniversity of Manitoba · CA

Funding

NORTH-WEST EUROPE INTERREG funded this research, grant number NWE 639, as part of the IDEA project (Implementation and development of economic viable algae-based value chains in Northwest Europe) 2017-2023. NWE 639
6 · The paper itself

Abstract

Inflammation, hypertension, and negative heart health outcomes including cardiovascular disease are closely linked but the mechanisms by which inflammation can cause high blood pressure are not yet fully elucidated. Cyclooxygenase (COX) enzymes play a role in pain, inflammation, and hypertension development, and inhibition of these enzymes is currently of great interest to researchers and pharmaceutical companies. Non-steroidal anti-inflammatory drugs are the drug of choice in terms of COX inhibition but can have negative side effects for consumers. Functional food ingredients containing cyclooxygenase inhibitors offer a strategy to inhibit cyclooxygenases without negative side effects. Several COX inhibitors have been discovered, to date, from marine and other resources. We describe here, for the first time, the generation and characterization of a bioactive hydrolysate generated using Viscozyme

Indexed as

HypertensionPorphyridiumAnimalsAntihypertensive AgentsCyclooxygenase 2Cyclooxygenase InhibitorsInflammationPainPeptidesRatsAntihypertensive AgentsCyclooxygenase 2Cyclooxygenase InhibitorsPeptidesanimal healthcyclooxygenase enzymeshypertensioninflammationpain reliefpeptidesPorphyridium sp.spontaneously hypertensive rats

Identifiers

PMID37623703
PMCPMC10456242
OpenAlexW4385319503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.