Evidence map›Paper›PMID 37623670›Full record

ReviewJournal of functional biomaterials2023

Drug Delivery Application of Functional Nanomaterials Synthesized Using Natural Sources.

Mekala Veerapandian, Subramaniyan Ramasundaram, Peter Jerome, Gayathri Chellasamy, Saravanan Govindaraju, Kyusik Yun, Tae Hwan Oh

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Metallo-herb complexes as emerging therapeutics: chemistry, synthesis approaches, and pharmacological insights.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mekala VeerapandianDepartment of Bionanotechnology, Gachon University, Soengnam 13120, Republic of Korea.
Subramaniyan RamasundaramSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38436, Republic of Korea.
Peter JeromeSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38436, Republic of Korea.
Gayathri ChellasamyDepartment of Bionanotechnology, Gachon University, Soengnam 13120, Republic of Korea.
Saravanan GovindarajuDepartment of Bionanotechnology, Gachon University, Soengnam 13120, Republic of Korea.ORCID 0000-0002-0411-9557
Kyusik YunDepartment of Bionanotechnology, Gachon University, Soengnam 13120, Republic of Korea.ORCID 0000-0002-6981-8113
Tae Hwan OhSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38436, Republic of Korea.ORCID 0000-0003-4922-5000

Funding

National Research Foundation of Korea 2022R1A2C1004283
6 · The paper itself

Abstract

Nanomaterials (NMs) synthesized from natural sources have been attracting greater attention, due to their intrinsic advantages including biocompatibility, stimuli-responsive property, nontoxicity, cost-effectiveness, and non-immunogenic characteristics in the biological environment. Among various biomedical applications, a breakthrough has been achieved in the development of drug delivery systems (DDS). Biocompatibility is necessary for treating a disease safely without any adverse effects. Some components in DDS respond to the physiological environment, such as pH, temperature, and functional group at the target, which facilitates targeted drug release. NM-based DDS is being applied for treating cancer, arthritis, cardiovascular diseases, and dermal and ophthalmic diseases. Metal nanomaterials and carbon quantum dots are synthesized and stabilized using functional molecules extracted from natural sources. Polymers, mucilage and gums, exosomes, and molecules with biological activities are directly derived from natural sources. In DDS, these functional components have been used as drug carriers, imaging agents, targeting moieties, and super disintegrants. Plant extracts, biowaste, biomass, and microorganisms have been used as the natural source for obtaining these NMs. This review highlights the natural sources, synthesis, and application of metallic materials, polymeric materials, carbon dots, mucilage and gums, and exosomes in DDS. Aside from that, challenges and future perspectives on using natural resources for DDS are also discussed.

Indexed as

carbon dotsdrug delivery system: metallic nanoparticlesexosomesmucilage and gumsnatural sourcespolymeric nanomaterials

Identifiers

PMID37623670
PMCPMC10455391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.