Evidence map›Paper›PMID 37623531›Full record

ReviewJournal of personalized medicine2023

Progress in Research on Stem Cells in Neonatal Refractory Diseases.

Fangjun Huang, Yang He, Meng Zhang, Keren Luo, Jiawen Li, Jiali Li, Xinyu Zhang, Xiaoyan Dong, Jun Tang

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fangjun HuangDepartment of Neonatology, West China Second Hospital, Sichuan University, Chengdu 610041, China.
Yang HeDepartment of Neonatology, West China Second Hospital, Sichuan University, Chengdu 610041, China.
Meng ZhangDepartment of Neonatology, West China Second Hospital, Sichuan University, Chengdu 610041, China.
Keren LuoDepartment of Neonatology, West China Second Hospital, Sichuan University, Chengdu 610041, China.
Jiawen LiDepartment of Neonatology, West China Second Hospital, Sichuan University, Chengdu 610041, China.
Jiali LiDepartment of Neonatology, West China Second Hospital, Sichuan University, Chengdu 610041, China.
Xinyu ZhangDepartment of Neonatology, West China Second Hospital, Sichuan University, Chengdu 610041, China.
Xiaoyan DongDepartment of Neonatology, West China Second Hospital, Sichuan University, Chengdu 610041, China.
Jun TangDepartment of Neonatology, West China Second Hospital, Sichuan University, Chengdu 610041, China.
Sichuan University · CNWest China Second University Hospital of Sichuan University · CN

Funding

West China Second University Hospital, Sichuan University Clinical Research Fund KL063
6 · The paper itself

Abstract

With the development and progress of medical technology, the survival rate of premature and low-birth-weight infants has increased, as has the incidence of a variety of neonatal diseases, such as hypoxic-ischemic encephalopathy, intraventricular hemorrhage, bronchopulmonary dysplasia, necrotizing enterocolitis, and retinopathy of prematurity. These diseases cause severe health conditions with poor prognoses, and existing control methods are ineffective for such diseases. Stem cells are a special type of cells with self-renewal and differentiation potential, and their mechanisms mainly include anti-inflammatory and anti-apoptotic properties, reducing oxidative stress, and boosting regeneration. Their paracrine effects can affect the microenvironment in which they survive, thereby affecting the biological characteristics of other cells. Due to their unique abilities, stem cells have been used in treating various diseases. Therefore, stem cell therapy may open up the possibility of treating such neonatal diseases. This review summarizes the research progress on stem cells and exosomes derived from stem cells in neonatal refractory diseases to provide new insights for most researchers and clinicians regarding future treatments. In addition, the current challenges and perspectives in stem cell therapy are discussed.

Indexed as

bronchopulmonary dysplasiacerebral intraventricular hemorrhagehypoxia–ischemianecrotizing enterocolitisretinopathy of prematuritystem cells

Identifiers

PMID37623531
PMCPMC10455340
OpenAlexW4386026727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.