Evidence map›Paper›PMID 37623514›Full record

ArticleJournal of personalized medicine2023

The Role of Oxidative Stress in Infertility.

Ioana Zaha, Mariana Muresan, Camelia Tulcan, Anca Huniadi, Petronela Naghi, Mircea Sandor, Roberta Tripon, Cristina Gaspar, Major Klaudia-Melinda, Liliana Sachelarie and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
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  10. Melatonin: a potential target for regulating ovarian function.Archives of gynecology and obstetrics · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ioana ZahaCalla-Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania.
Mariana MuresanFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Camelia TulcanFaculty of Engineering and Applied Technologies, University of Life Sciences "King Michael I of Romania", 300645 Timisoara, Romania.ORCID 0000-0003-3096-0232
Anca HuniadiCalla-Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania.ORCID 0000-0002-5998-9488
Petronela NaghiCalla-Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania.ORCID 0000-0002-1440-3965
Mircea SandorFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0001-8967-0059
Roberta TriponFaculty of Engineering and Applied Technologies, University of Life Sciences "King Michael I of Romania", 300645 Timisoara, Romania.ORCID 0000-0003-4913-8740
Cristina GasparFaculty of Engineering and Applied Technologies, University of Life Sciences "King Michael I of Romania", 300645 Timisoara, Romania.
Major Klaudia-MelindaSzabolcs-Szatmar Bereg County Hospital and University Centre, Jose Andras Hospital, 4400 Nyireghyhaza, Hungary.
Liliana SachelarieDepartment of Prelinical Discipline, Apollonia University, 700511 Iasi, Romania.ORCID 0000-0001-7701-2307
Liana StefanCalla-Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania.
University of Oradea · ROApollonia University · ROJósa András Múzeum · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Oxidative stress markers in the follicular fluid and serum of the patient with IVF results (number of fertilized oocytes, number of embryos, cumulative pregnancy rate) are important in establishing the causes of infertility. (2) Methods: 42 patients were enrolled in the study over the duration of 24 months and were divided into two groups: the study group divided into the female etiology for infertility as a tubal factor, diminished ovarian reserve, endometriosis, and unexplained infertility, and the control group consisting of the male factor, excluding the sperm donors and with no female factor cause. On the day of ovarian puncture in IVF, follicular fluid and serum were collected from the patients. (3) Results: Malondialdehyde from the follicular fluid was higher in the control group. The total antioxidant capacity in the follicular fluid is positively correlated with the pregnancy rate. There is no statistically significant difference in the oxidative stress markers from serum in both groups. (4) Conclusions: The capacity of the follicular fluid environment to contain the reactive oxygen species (ROS) leads to a higher pregnancy rate in the control group.

Indexed as

antioxidant capacityfollicular fluidIVFoxidative stressserum

Identifiers

PMID37623514
PMCPMC10455473
OpenAlexW4385840486

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.