Evidence map›Paper›PMID 37623503›Full record

ReviewJournal of personalized medicine2023

Unlocking the Potential of Mesenchymal Stem Cells in Gynecology: Where Are We Now?

Ivana Erceg Ivkošić, Rajko Fureš, Vesna Ćosić, Nika Mikelin, Luka Bulić, Domagoj Dobranić, Petar Brlek, Dragan Primorac

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Application of adult stem cells in obstetrics and gynecology: A scoping review.European journal of obstetrics & gynecology and reproductive biology: X · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Ivana Erceg IvkošićSt. Catherine Specialty Hospital, 10000 Zagreb, Croatia.
Rajko FurešFaculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia.
Vesna ĆosićFaculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia.
Nika MikelinHealth Center of the Zagreb County, 10000 Zagreb, Croatia.
Luka BulićSt. Catherine Specialty Hospital, 10000 Zagreb, Croatia.ORCID 0000-0001-6522-891X
Domagoj DobranićSt. Catherine Specialty Hospital, 10000 Zagreb, Croatia.
Petar BrlekSt. Catherine Specialty Hospital, 10000 Zagreb, Croatia.ORCID 0000-0001-8022-4095
Dragan PrimoracSt. Catherine Specialty Hospital, 10000 Zagreb, Croatia.ORCID 0000-0001-5565-080X
University of Osijek · HRLee College · USUniversity of Slavonski Brod · HRZabok General Hospital · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cells, with their remarkable capacity for differentiation into diverse cell types, are vital for the development as well as maintenance of health and homeostasis. Two unique abilities set them apart from other cells: self-renewal and the capacity for differentiation. They play important roles in embryogenesis, development, regeneration, and various other processes. Over the last decade, there has been increased interest in their potential use in the treatment of numerous diseases and disorders across multiple fields of medicine in acute, chronic, innate, and acquired diseases. Stem cells are key to maintaining the body's homeostasis and regulating growth and tissue functions. There are several types of stem cells-embryonic, adult, and human-induced pluripotent cells. Currently, mesenchymal stem cells are of great interest due to their regenerative, immunomodulatory, analgesic, and antimicrobial (anti-inflammatory) effects. Recent studies have shown the potent regenerative effect of stem cell therapy in gynecologic diseases such as infertility, Asherman syndrome, lichen sclerosus, polycystic ovary syndrome, premature ovarian insufficiency, genitourinary syndrome of menopause, and rectovaginal fistulas. Moreover, the successful isolation of oogonial stem cells could lead to a revolution in the field of gynecology and the potential treatment of the conditions discussed. This review aims to provide a better understanding of the latest therapeutic options involving stem cells and raise awareness of this promising yet not widely known topic in gynecology and medicine in general.

Indexed as

genitourinary syndrome of menopausegynecologyinfertilitylichen sclerosusmesenchymal stem cellpolycystic ovary syndromepremature ovarian insufficiencyrectovaginal fistularegenerative medicine

Identifiers

PMID37623503
PMCPMC10455325
OpenAlexW4385812727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.