Evidence map›Paper›PMID 37623492›Full record

ArticleJournal of personalized medicine2023

Discovery of Biomarkers Related to Interstitial Fibrosis and Tubular Atrophy among Kidney Transplant Recipients by mRNA-Sequencing.

Hyun Kyung Lee, Na Hyun Jung, Da Eun Lee, Hajeong Lee, Jaeseok Yang, Yon Su Kim, Seung Seok Han, Nayoung Han, In-Wha Kim, Jung Mi Oh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hyun Kyung LeeCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Na Hyun JungCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Da Eun LeeCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Hajeong LeeDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Republic of Korea.ORCID 0000-0002-1873-1587
Jaeseok YangTransplantation Center, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Yon Su KimDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Seung Seok HanDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Nayoung HanCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
In-Wha KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0003-4976-3343
Jung Mi OhCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Seoul National University · KRYonsei University · KR

Funding

National Research Foundation of Korea NRF-2019R1A2C1005211
6 · The paper itself

Abstract

Interstitial fibrosis and tubular atrophy (IF/TA) after kidney transplantation causes a chronic deterioration of graft function. IF/TA can be diagnosed by means of a graft biopsy, which is a necessity as non-invasive diagnostic methods are unavailable. In this study, we identified IF/TA-related differentially expressed genes (DEGs) through next-generation sequencing using peripheral blood mononuclear cells. Blood samples from kidney transplant recipients undergoing standard immunosuppressive therapy (tacrolimus/mycophenolate mofetil or mycophenolate sodium/steroid) and diagnosed as IF/TA (

Indexed as

differentially expressed geneinterstitial fibrosis and tubular atrophykidney transplantationmRNA-sequencingperipheral blood mononuclear cell

Identifiers

PMID37623492
PMCPMC10455123
OpenAlexW4385741282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.