Evidence map›Paper›PMID 37623454›Full record

ArticleJournal of personalized medicine2023

Primary Thyroid Lymphoma: How Molecular Biology and Ancillary Techniques Can Help the Cytopathologist Overcome This Diagnostic Challenge.

Leo Guidobaldi, Concetta Cafiero, Gerardo D'Amato, Marco Dell'Aquila, Pierpaolo Trimboli, Raffaele Palmirotta, Salvatore Pisconti

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Leo GuidobaldiCytodiagnostic Unit, Section of Pathology Sandro Pertini Hospital, ASL RM2, 00157 Rome, RM, Italy.ORCID 0000-0002-8205-3645
Concetta CafieroMedical Oncology, SG Moscati Hospital, 74010 Statte, TA, Italy.ORCID 0000-0002-1401-8020
Gerardo D'AmatoDipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli Federico II, 80131 Naples, NA, Italy.
Marco Dell'AquilaPathology Unit, Belcolle Hospital, ASL Viterbo, 01100 Viterbo, VT, Italy.ORCID 0000-0001-5673-6998
Pierpaolo TrimboliServizio di Endocrinologia e Diabetologia, Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.ORCID 0000-0002-2125-4937
Raffaele PalmirottaInterdisciplinary Department of Medicine, School of Medicine, University of Bari "Aldo Moro", 70124 Bari, BA, Italy.ORCID 0000-0002-9401-7377
Salvatore PiscontiMedical Oncology, SG Moscati Hospital, 74010 Statte, TA, Italy.
Azienda Ospedaliera S.Giuseppe Moscati · ITEnte Ospedaliero Cantonale · CHOspedale di Belcolle · ITOspedale Sandro Pertini · ITUniversity of Bari Aldo Moro · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary thyroid lymphoma (PTL) occurs rarely, its diagnosis is a challenge, and the prognosis of these patients depends on the time of diagnosis. Even though fine-needle aspiration cytology (FNAC) is recognized as the most accurate tool for detecting thyroid malignancies, its sensitivity for PTL is poor. Both clinical and ultrasound presentation of PTL can be atypical, and laboratory tests fail to furnish relevant data. Consequently, the reliability of a cytopathologist facing PTL can be poor, even when he is aware of its clinical information. In addition, the cases described in the literature are extremely rare and fragmentary, and consequently, the molecular data currently available for this neoplasm are practically negligible. Here, we present a case report in order to discuss the intrinsic limitations in achieving a final diagnosis of PTL and how using molecular diagnostics to identify potential mutational models can improve the evaluation of this neoplasm.

Indexed as

cytologyfine-needle aspirationmalignant lymphomathyroid

Identifiers

PMID37623454
PMCPMC10455942
OpenAlexW4385423261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.