Evidence map›Paper›PMID 37623267›Full record

ReviewClinics and practice2023

Past, Current, and Future Perspectives on Transplanting Acute Kidney Injury Kidneys.

Rachana Punukollu, Margaret Ryan, Suman Misra, Pooja Budhiraja, Stephanie Ohara, Kayla Kumm, Giselle Guerra, Kunam S Reddy, Raymond Heilman, Caroline C Jadlowiec

Open access · goldAbstract readReview
In one paragraph

Review in Clinics and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rachana PunukolluDivision of Transplant Surgery, Department of Surgery, Mayo Clinic, Phoenix, AZ 85054, USA.ORCID 0000-0002-4401-4127
Margaret RyanDivision of Anatomic Pathology, Mayo Clinic, Phoenix, AZ 85054, USA.
Suman MisraDivision of Nephrology, Mayo Clinic, Phoenix, AZ 85054, USA.
Pooja BudhirajaDivision of Nephrology, Mayo Clinic, Phoenix, AZ 85054, USA.
Stephanie OharaDivision of Surgery, Valleywise Health Medical Center, Creighton University, Phoenix, AZ 85008, USA.
Kayla KummDivision of Transplant Surgery, Department of Surgery, Mayo Clinic, Phoenix, AZ 85054, USA.
Giselle GuerraDivision of Nephrology, Miami Transplant Institute, Miami, FL 33136, USA.
Kunam S ReddyDivision of Transplant Surgery, Department of Surgery, Mayo Clinic, Phoenix, AZ 85054, USA.
Raymond HeilmanDivision of Nephrology, Mayo Clinic, Phoenix, AZ 85054, USA.
Caroline C JadlowiecDivision of Transplant Surgery, Department of Surgery, Mayo Clinic, Phoenix, AZ 85054, USA.ORCID 0000-0001-7860-9519
WinnMed · USCHI Health Creighton University Medical Center - Bergan Mercy · USMayo Clinic Hospital · USMiami Transplant Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Acute kidney injury (AKI) kidneys have high non-utilization rates due to concerns regarding unfavorable outcomes. In this paper, we aimed to review the past, present, and future opinions on AKI kidneys. (2) Methods: A PubMed search was conducted for topics relevant to AKI kidney transplantation. (3) Results: Current short- and long-term data on AKI kidneys have demonstrated good outcomes including favorable graft function and survival. The role of procurement biopsies is controversial, but they have been shown to be beneficial in AKI kidneys by allowing clinicians to differentiate between reversible tubular injury and irreversible cortical necrosis. Machine perfusion has also been applied to AKI kidneys and has been shown to reduce delayed graft function (DGF). The incidence of DGF increases with AKI severity and its management can be challenging. Strategies employed to counteract this have included early initiation of dialysis after kidney transplantation, early targeting of adequate immunosuppression levels to minimize rejection risk, and establishment of outpatient dialysis. (4) Conclusions: Despite good outcomes, there continue to be barriers that impact AKI kidney utilization. Successful strategies have included use of procurement biopsies or machine perfusion and expectant management of DGF. With increasing experience, better use of AKI kidneys can result in additional opportunities to expand the donor pool.

Indexed as

acute kidney injurydelayed graft functiondonor poolkidney transplantorgan shortage

Identifiers

PMID37623267
PMCPMC10453697
OpenAlexW4385802315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.