Evidence map›Paper›PMID 37623251›Full record

ArticleCurrent issues in molecular biology2023

Denisse Stephania Becerra-Loaiza, Luisa Fernanda Roldan Flores, Luis Antonio Ochoa-Ramírez, Bricia M Gutiérrez-Zepeda, Alicia Del Toro-Arreola, Ramón Antonio Franco-Topete, Andrés Morán-Mendoza, Antonio Oceguera-Villanueva, Antonio Topete, David Javalera and 2 more

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Denisse Stephania Becerra-LoaizaCentro Universitario de Ciencias de la Salud, Laboratorio de Inmunología, Departamento de Fisiología, Universidad de Guadalajara, Sierra Mojada #950, Guadalajara 44340, Mexico.
Luisa Fernanda Roldan FloresCentro Universitario de Ciencias de la Salud, Laboratorio de Inmunología, Departamento de Fisiología, Universidad de Guadalajara, Sierra Mojada #950, Guadalajara 44340, Mexico.
Luis Antonio Ochoa-RamírezLaboratorio de Medicina Genómica, Hospital General de Culiacán, Culiacán 80230, Mexico.
Bricia M Gutiérrez-ZepedaCentro Universitario de Ciencias de la Salud, Laboratorio de Inmunología, Departamento de Fisiología, Universidad de Guadalajara, Sierra Mojada #950, Guadalajara 44340, Mexico.ORCID 0000-0002-9239-665X
Alicia Del Toro-ArreolaCentro Universitario de Ciencias de la Salud, Laboratorio de Inmunología, Departamento de Fisiología, Universidad de Guadalajara, Sierra Mojada #950, Guadalajara 44340, Mexico.
Ramón Antonio Franco-TopeteCentro Universitario de Ciencias de la Salud, Laboratorio de Patología, Departamento de Microbiología y Patología, Universidad de Guadalajara, Sierra Mojada #950, Guadalajara 44340, Mexico.
Andrés Morán-MendozaCentro Médico Nacional de Occidente, Hospital de Gineco Obstetricia, Instituto Mexicano del Seguro Social, Av. Belisario Domínguez #1000, Guadalajara 44340, Mexico.
Antonio Oceguera-VillanuevaInstituto Jalisciense de Cancerología, Secretaría de Salud, Coronel Calderón #715, Guadalajara 44280, Mexico.
Antonio TopeteCentro Universitario de Ciencias de la Salud, Laboratorio de Inmunología, Departamento de Fisiología, Universidad de Guadalajara, Sierra Mojada #950, Guadalajara 44340, Mexico.
David JavaleraDepartamento de Aparatos y Sistemas II, Universidad Autónoma de Guadalajara, Av. Patria #1201, Zapopan 45129, Mexico.
Antonio Quintero-RamosCentro Universitario de Ciencias de la Salud, Laboratorio de Inmunología, Departamento de Fisiología, Universidad de Guadalajara, Sierra Mojada #950, Guadalajara 44340, Mexico.ORCID 0000-0001-5963-9712
Adrián Daneri-NavarroCentro Universitario de Ciencias de la Salud, Laboratorio de Inmunología, Departamento de Fisiología, Universidad de Guadalajara, Sierra Mojada #950, Guadalajara 44340, Mexico.
Universidad de Guadalajara · MXMexican Social Security Institute · MXSecretaria de Salud · MXUniversidad Autónoma de Guadalajara · MX

Funding

University of Guadalajara PRO-SNI 2020/2021
6 · The paper itself

Abstract

HLA-G is a physiology and pathologic immunomodulator detrimentally related to cancer. Its gene is heavily transcriptionally and post-transcriptionally regulated by variants located in regulator regions like 3'UTR, being the most studied Ins/Del of 14-bp (rs66554220), which is known to influence the effects of endogen cell factors; nevertheless, the reports are discrepant and controversial. Herein, the relationship of the 14-bp Ins/Del variant (rs66554220) with breast cancer (BC) and its clinical characteristics were analyzed in 182 women with non-familial BC and 221 disease-free women as a reference group. Both groups from western Mexico and sex-age-matched (sm-RG). The rs66554220 variant was amplified by SSP-PCR and the fragments were visualized in polyacrylamide gel electrophoresis. The variant rs66554220 was not associated with BC in our population. However, we suggest the Ins allele as a possible risk factor for developing BC at clinical stage IV (OR = 3.05, 95% CI = 1.16-7.96,

Indexed as

14-bp Ins/Delbreast cancerclinicalHLA-GMexican populationrs66554220stage IVwestern Mexico

Identifiers

PMID37623251
PMCPMC10453716
OpenAlexW4385872450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.