Evidence map›Paper›PMID 37623127›Full record

ArticleGels (Basel, Switzerland)2023

Bromelain- and Silver Nanoparticle-Loaded Polycaprolactone/Chitosan Nanofibrous Dressings for Skin Wound Healing.

Yasaman Saghafi, Hadi Baharifar, Najmeh Najmoddin, Azadeh Asefnejad, Hassan Maleki, Sayed Mahmoud Sajjadi-Jazi, Alireza Bonkdar, Forough Shams, Kamyar Khoshnevisan

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yasaman SaghafiDepartment of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran 1477893855, Iran.
Hadi BaharifarDepartment of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran 1477893855, Iran.ORCID 0000-0002-8913-3672
Najmeh NajmoddinDepartment of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran 1477893855, Iran.
Azadeh AsefnejadDepartment of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran 1477893855, Iran.ORCID 0000-0002-0274-4180
Hassan MalekiResearch and Development Team, Evolution Wound Dressing (EWD) Startup Co., Tehran 1983963113, Iran.
Sayed Mahmoud Sajjadi-JaziResearch and Development Team, Evolution Wound Dressing (EWD) Startup Co., Tehran 1983963113, Iran.
Alireza BonkdarMedical Nanotechnology and Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, Iran.
Forough ShamsDepartment of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, Iran.
Kamyar KhoshnevisanResearch and Development Team, Evolution Wound Dressing (EWD) Startup Co., Tehran 1983963113, Iran.ORCID 0000-0003-1250-4292
Islamic Azad University, Science and Research Branch · IRShahid Beheshti University of Medical Sciences · IRKermanshah University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A cutaneous wound is caused by various injuries in the skin, which can be wrapped with an efficient dressing. Electrospinning is a straightforward adjustable technique that quickly and continuously generates nanofibrous wound dressings containing antibacterial and anti-inflammatory agents to promote wound healing. The present study investigated the physicochemical and biological properties of bromelain (BRO)- and silver nanoparticle (Ag NPs)-loaded gel-based electrospun polycaprolactone/chitosan (PCL/CS) nanofibrous dressings for wound-healing applications. Electron microscopy results showed that the obtained nanofibers (NFs) had a uniform and homogeneous morphology without beads with an average diameter of 176 ± 63 nm. The FTIR (Fourier transform infrared) analysis exhibited the loading of the components. Moreover, adding BRO and Ag NPs increased the tensile strength of the NFs up to 4.59 MPa. BRO and Ag NPs did not significantly affect the hydrophilicity and toxicity of the obtained wound dressing; however, the antibacterial activity against

Indexed as

bromelainchitosanelectrospinningnanofiberspolycaprolactonesilver nanoparticleswound dressing

Identifiers

PMID37623127
PMCPMC10454236
OpenAlexW4386028421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.