ArticleGels (Basel, Switzerland)2023
Composite Hydrogels with Embedded Silver Nanoparticles and Ibuprofen as Wound Dressing.
Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Integrating silver nanomaterials in wound healing: from physicochemical properties to clinical translation.Journal of nanobiotechnology · 2026Review
- Chitosan-Based Adhesive Composite Hydrogel to Provide Antibacterial and Anti-Inflammatory Properties for Biomedical Application.Gels (Basel, Switzerland) · 2026Article
- Polysaccharide based biomaterials for advanced wound healing applications.Frontiers in cellular and infection microbiology · 2026Review
- Substance-Based Medical Device in Wound Care: Bridging Regulatory Clarity and Therapeutic Innovation.Polymers · 2025Review
- Topical Use of Sucralfate in Cutaneous Wound Management: A Narrative Review with a Veterinary Perspective.Veterinary sciences · 2025Review
- Development and Characterization of Polymer Blends Based on Polyvinyl Alcohol for Application as Pharmaceutical Dosage Form.Polymers · 2025Article
- Dual-Drug Delivery Systems Using Hydrogel-Nanoparticle Composites: Recent Advances and Key Applications.Gels (Basel, Switzerland) · 2025Review
- Biotechnological Utilization of Amazonian Fruit: Development of Active Nanocomposites from Bacterial Cellulose and Silver Nanoparticles Based onPharmaceuticals (Basel, Switzerland) · 2025Article
- Superior In Vivo Wound-Healing Activity of Biosynthesized Silver Nanoparticles with Nepeta cataria (Catnip) on Excision Wound Model in Rat.Biological trace element research · 2025Article
- Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings.Gels (Basel, Switzerland) · 2025Review
- The Use of AgNP-Containing Nanocomposites Based on Galactomannan and κ-Carrageenan for the Creation of Hydrogels with Antiradical Activity.Gels (Basel, Switzerland) · 2024Article
- Multifunctional Ag-Poly(Polymers · 2024Article
- Development of Polyvinyl Alcohol Hydrogels for Controlled Glucose Release in Biomedical Applications.Gels (Basel, Switzerland) · 2024Article
- Recent Advances in Poly(vinyl alcohol)-Based Hydrogels.Polymers · 2024Review
- Topical Meloxicam Hydroxypropyl Guar Hydrogels Based on Low-Substituted Hydroxypropyl Cellulose Solid Dispersions.Gels (Basel, Switzerland) · 2024Article
- Thermosensitive Hydrogel-Functionalized Mesoporous Silica Nanoparticles for Parenteral Application of Chemotherapeutics.Gels (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The wound healing process is often slowed down as a result of complications from bacterial infections and inflammatory reactions. Therefore, it is necessary to develop dressings with fast antibacterial and anti-inflammatory activity that shorten the wound healing period by promoting cell migration and proliferation. Chitosan (CS)-based hydrogels have been widely studied for their antibacterial and wound healing capabilities. Herein, we developed a composite hydrogel based on CS and PVA embedding silver nanoparticles (AgNPs) with antibacterial properties and ibuprofen (Ib) as an anti-inflammatory agent. The hydrogel prepared by double physical cross-linking, with oxalic acid and by freeze-thawing, loaded with 0.225 wt.% AgNPs and 0.264 wt.% Ib, displayed good mechanical properties (compressive modulus = 132 kPa), a high swelling degree and sustained drug delivery (in simulated skin conditions). Moreover, the hydrogel showed strong antibacterial activity against
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Registered trials
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