Evidence map›Paper›PMID 37623039›Full record

ArticleCurrent oncology (Toronto, Ont.)2023

Impact of Oncology Drug Review Times on Public Funding Recommendations.

Marya Hussain, Chelsea Wong, Eddy Taguedong, Saurav Verma, Md Mahsin, Safiya Karim, Richard Lee-Ying, Doreen A Ezeife

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Marya HussainDepartment of Oncology, University of Calgary, Calgary, AB T2N 4N2, Canada.ORCID 0000-0003-1659-0423
Chelsea WongFaculty of Arts, Department of Psychology, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-4795-4982
Eddy TaguedongDepartment of Medicine, McGill University, Montreal, QC H3A 0G4, Canada.
Saurav VermaLondon Regional Cancer Program, Department of Medical Oncology, London Health Sciences Centre, London, ON N6A 5W9, Canada.ORCID 0000-0002-8841-9820
Md MahsinPrecision Oncology Hub, Alberta Health Services, Calgary, AB T2N 4Z6, Canada.ORCID 0000-0002-0422-6010
Safiya KarimDepartment of Oncology, University of Calgary, Calgary, AB T2N 4N2, Canada.
Richard Lee-YingDepartment of Oncology, University of Calgary, Calgary, AB T2N 4N2, Canada.
Doreen A EzeifeDepartment of Oncology, University of Calgary, Calgary, AB T2N 4N2, Canada.
University of Calgary · CAAlberta Health Services · CAMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New oncology drugs undergo detailed review prior to public funding in a single-payer healthcare system. The aim of this study was to assess how cancer drug review times impact funding recommendations. Drugs reviewed by the pan-Canadian Oncology Drug Review (pCODR) between the years 2012 and 2020 were included. Data were collected including Health Canada approval dates, initial and final funding recommendations, treatment intent, drug class, clinical indications, and incremental cost-effectiveness ratios (ICER). Univariable and multivariable analyses were used to determine the association between funding recommendations and review times. Of the 164 applications submitted, 130 received a positive final recommendation. Median time from Health Canada (HC) approval to final recommendation was longer for drugs indicated for the treatment of gastrointestinal (GI) and lung cancer compared to breast, genitourinary (GU), and other tumours (205 vs. 198 vs. 111 vs. 129 vs. 181 days, respectively; Kruskal-Wallis

Indexed as

Drug Utilization ReviewMedical OncologyCanadaHumansLung NeoplasmsSingle-Payer SystemCanadian Agency for Drugs and Technologies in Health (CADTH)drug approval timeoncology drug reviewoncology drugs

Identifiers

PMID37623039
PMCPMC10453657
OpenAlexW4385978978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.