Evidence map›Paper›PMID 37622865›Full record

ArticleBiosensors2023

Fluoropolymer Functionalization of Organ-on-Chip Platform Increases Detection Sensitivity for Cannabinoids.

Ziqiu Tong, Lars Esser, Peter Galettis, David Rudd, Christopher D Easton, Azadeh Nilghaz, Bo Peng, Douer Zhu, Helmut Thissen, Jennifer H Martin and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Ziqiu TongDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Lars EsserCommonwealth Scientific and Industrial Research Organisation (CSIRO), Clayton, VIC 3168, Australia.ORCID 0000-0002-5511-5281
Peter GalettisCentre for Drug Repurposing & Medicines Research, School of Medicine and Public Health, Faculty of Health, Medicine & Wellbeing, The University of Newcastle, Callaghan, NSW 2308, Australia.ORCID 0000-0002-6785-2529
David RuddDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.ORCID 0000-0003-3104-309X
Christopher D EastonCommonwealth Scientific and Industrial Research Organisation (CSIRO), Clayton, VIC 3168, Australia.ORCID 0000-0002-1981-3779
Azadeh NilghazDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Bo PengDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Douer ZhuDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Helmut ThissenCommonwealth Scientific and Industrial Research Organisation (CSIRO), Clayton, VIC 3168, Australia.ORCID 0000-0002-3254-6855
Jennifer H MartinCentre for Drug Repurposing & Medicines Research, School of Medicine and Public Health, Faculty of Health, Medicine & Wellbeing, The University of Newcastle, Callaghan, NSW 2308, Australia.ORCID 0000-0002-8614-0199
Nicolas H VoelckerDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.ORCID 0000-0002-1536-7804
Commonwealth Scientific and Industrial Research Organisation · AUMonash University · AUHunter Medical Research Institute · AUDeakin University · AUMelbourne Centre for Nanofabrication · AUNorthwestern Polytechnical University · CN

Funding

Australian Research Council IC70100016
6 · The paper itself

Abstract

Microfluidic technology is applied across various research areas including organ-on-chip (OOC) systems. The main material used for microfluidics is polydimethylsiloxane (PDMS), a silicone elastomer material that is biocompatible, transparent, and easy to use for OOC systems with well-defined microstructures. However, PDMS-based OOC systems can absorb hydrophobic and small molecules, making it difficult and erroneous to make quantitative analytical assessments for such compounds. In this paper, we explore the use of a synthetic fluoropolymer, poly(4,5-difluoro-2,2-bis(trifluoromethyl)-1,3-dioxole-

Indexed as

CannabidiolCannabinoidsChromatography, LiquidDimethylpolysiloxanesEndothelial CellsFluorocarbon PolymersTandem Mass SpectrometrybaysilonCannabidiolCannabinoidsDimethylpolysiloxanesFluorocarbon Polymerscannabidiolcannabinoidsdetection sensitivitymicrofluidicsorgan-on-chip systemstetrafluoroethylene

Identifiers

PMID37622865
PMCPMC10452156
OpenAlexW4385446726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.