Evidence map›Paper›PMID 37622005›Full record

ArticleiScience2023

Preservation of whole antibodies within ancient teeth.

Barry Shaw, Thomas McDonnell, Elizabeth Radley, Brian Thomas, Lynn Smith, Carol A L Davenport, Silvia Gonzalez, Anisur Rahman, Rob Layfield

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Barry ShawSchool of Life Sciences, University of Nottingham Medical School, Nottingham, UK.
Thomas McDonnellCentre for Rheumatology Research, Division of Medicine, UCL, London, UK.
Elizabeth RadleyDepartment of Biochemistry, University of Toronto, Toronto, Canada.
Brian ThomasMass Spectrometry Research Group, University of Liverpool, Liverpool, UK.
Lynn SmithNorton Priory Museum and Gardens, Runcorn, UK.
Carol A L DavenportResearch Centre for Evolutionary Anthropology and Paleoecology, Liverpool John Moores University, Liverpool, UK.
Silvia GonzalezResearch Centre for Evolutionary Anthropology and Paleoecology, Liverpool John Moores University, Liverpool, UK.
Anisur RahmanCentre for Rheumatology Research, Division of Medicine, UCL, London, UK.
Rob LayfieldSchool of Life Sciences, University of Nottingham Medical School, Nottingham, UK.
Liverpool John Moores University · GBUniversity of Nottingham · GBBritish Society for Rheumatology · GBNorton Priory Museum & Gardens · GBUniversity College London · GBUniversity of Liverpool · GBUniversity of Toronto · CA

Funding

MRF_ MRF-057-0004-RG-MCDO-C0800MRF_ MRF-159-0006-ELP-MCDO-C0954Versus Arthritis 22977
6 · The paper itself

Abstract

Archaeological remains can preserve some proteins into deep time, offering remarkable opportunities for probing past events in human history. Recovering functional proteins from skeletal tissues could uncover a molecular memory related to the life-history of the associated remains. We demonstrate affinity purification of whole antibody molecules from medieval human teeth, dating to the 13

Indexed as

Biological sciencesPaleobiochemistryPaleobiology

Identifiers

PMID37622005
PMCPMC10445445
OpenAlexW4385704223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.