Evidence map›Paper›PMID 37621847›Full record

ArticleFuture science OA2023

Establishment of cancer cell line originating from a patient with high-grade serous ovarian carcinoma.

Nguyen Thuy Linh, Ngo Thu Hang, Bui Khac Cuong, Dang Thuy Linh, Nham Thi Phuong Linh, Do Nguyen-Van, Tran Ngoc Dzung, Can Van Mao, Dang Thanh Chung, Le Tri Chinh and 3 more

Open access · goldAbstract read
In one paragraph

Article in Future science OA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Nguyen Thuy LinhDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi, Vietnam.ORCID https://orcid.org/0000-0003-4326-1991
Ngo Thu HangDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi, Vietnam.
Bui Khac CuongDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi, Vietnam.ORCID https://orcid.org/0000-0002-5781-5898
Dang Thuy LinhDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi, Vietnam.
Nham Thi Phuong LinhLaboratory Animal Research Center, Vietnam Military Medical University, Hanoi, Vietnam.
Do Nguyen-VanDepartment of Pathophysiology & Immunology, Hanoi Medical University, Hanoi, Vietnam.
Tran Ngoc DzungDepartment of Pathology, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam.
Can Van MaoDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi, Vietnam.
Dang Thanh ChungDepartment of Pathology, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam.ORCID https://orcid.org/0000-0003-2376-1665
Le Tri ChinhDepartment of Gynaecology Surgery, Vietnam National Cancer Hospital, Hanoi, Vietnam.
Nguyen Phu HungFaculty of Biotechnology, Thai Nguyen University of Sciences, Thai Nguyen, Vietnam.
Hoang Van TongDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi, Vietnam.ORCID https://orcid.org/0000-0002-7170-8810
Nguyen Linh ToanDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi, Vietnam.ORCID https://orcid.org/0000-0001-7850-3896
Vietnam Military Medical University · VNHanoi Medical University · VNThai Nguyen University · VNVietnam National Children's Hospital · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Ovarian cancer is a serious malignancy with high prevalence and mortality. Methods: We isolated and characterized an ovarian high-grade serous cancer cell line (M4) from a tumor of a Vietnamese patient with ovarian carcinoma. Results: The M4 cancer cell line showed good proliferation and stability in culture. Morphologically, the M4 cells showed similar characteristics to tumor cells such as a polyhedral shape, large irregular nuclei, high nuclear/cytoplasmic ratio, high nuclear density and expressing cancer markers like CA125, p53 and Ki67 markers. Conclusion: We have successfully isolated and characterized the M4 cell line from a Vietnamese patient with ovarian carcinoma.

Indexed as

CD46cell linehigh-grade serous carcinomaimmunohistochemistryovarian cancer

Identifiers

PMID37621847
PMCPMC10445588
OpenAlexW4385380379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.