Evidence map›Paper›PMID 37621704›Full record

ArticleFrontiers in genetics2023

Natural selection shapes the evolution of SARS-CoV-2 Omicron in Bangladesh.

Mohammad Tanbir Habib, Saikt Rahman, Mokibul Hassan Afrad, Arif Mahmud Howlader, Manjur Hossain Khan, Farhana Khanam, Ahmed Nawsher Alam, Emran Kabir Chowdhury, Ziaur Rahman, Mustafizur Rahman and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Mitogenomic analysis ofFrontiers in veterinary science · 2026
    Article
  3. COVID-19 mutations: An overview.World journal of methodology · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Mohammad Tanbir HabibInstitute for Developing Science and Health Initiatives, Dhaka, Bangladesh.
Saikt RahmanInstitute for Developing Science and Health Initiatives, Dhaka, Bangladesh.
Mokibul Hassan AfradInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Arif Mahmud HowladerInstitute for Developing Science and Health Initiatives, Dhaka, Bangladesh.
Manjur Hossain KhanInstitute of Epidemiology, Disease Control and Research, Dhaka, Bangladesh.
Farhana KhanamInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Ahmed Nawsher AlamInstitute of Epidemiology, Disease Control and Research, Dhaka, Bangladesh.
Emran Kabir ChowdhuryDepartment of Biochemistry and Molecular Biochemistry, University of Dhaka, Dhaka, Bangladesh.
Ziaur RahmanInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Mustafizur RahmanInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Tahmina ShirinInstitute of Epidemiology, Disease Control and Research, Dhaka, Bangladesh.
Firdausi QadriInstitute for Developing Science and Health Initiatives, Dhaka, Bangladesh.
Bangladesh Institute of Development Studies · BDInternational Centre for Diarrhoeal Disease Research · BDInstitute of Epidemiology, Disease Control and Research · BDUniversity of Dhaka · BD

Funding

Training program in vaccine development and public healthD43TW005572 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI QADRI, FIRDAUSI, RYAN, EDWARD T. · 2000 to 2025
$5.4M
FIC NIH HHS D43 TW005572Wellcome Trust
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved to give rise to a highly transmissive and immune-escaping variant of concern, known as Omicron. Many aspects of the evolution of SARS-CoV-2 and the driving forces behind the ongoing Omicron outbreaks remain unclear. Substitution at the receptor-binding domain (RBD) in the spike protein is one of the primary strategies of SARS-CoV-2 Omicron to hinder recognition by the host angiotensin-converting enzyme 2 (ACE2) receptor and avoid antibody-dependent defense activation. Here, we scanned for adaptive evolution within the SARS-CoV-2 Omicron genomes reported from Bangladesh in the public database GISAID (www.gisaid.org; dated 2 April 2023). The ratio of the non-synonymous (

Indexed as

adaptive evolutionBangladeshcodon substitutionKa/KsOmicronSARS-CoV-2spike proteinω

Identifiers

PMID37621704
PMCPMC10446972
OpenAlexW4385693674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.