Evidence map›Paper›PMID 37620860›Full record

ArticleCell communication and signaling : CCS2023

Calcineurin stimulation by Cnb1p overproduction mitigates protein aggregation and α-synuclein toxicity in a yeast model of synucleinopathy.

Srishti Chawla, Doryaneh Ahmadpour, Kara L Schneider, Navinder Kumar, Arthur Fischbach, Mikael Molin, Thomas Nystrom

Open access · goldAbstract readVideo-Audio Media
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell communication and signaling : CCS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Elimination of virus-like particles reduces protein aggregation and extends replicative lifespan inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Srishti ChawlaInstitute for Biomedicine, Sahlgrenska Academy, Centre for Ageing and Health - AgeCap, University of Gothenburg, Gothenburg, 405 30, Sweden. srishti@chalmers.se.
Doryaneh AhmadpourCenter for Bionics and Pain Research, Sahlgrenska University Hospital, Mölndal, 431 30, Sweden.
Kara L SchneiderInstitute for Biomedicine, Sahlgrenska Academy, Centre for Ageing and Health - AgeCap, University of Gothenburg, Gothenburg, 405 30, Sweden.
Navinder KumarInstitute for Biomedicine, Sahlgrenska Academy, Centre for Ageing and Health - AgeCap, University of Gothenburg, Gothenburg, 405 30, Sweden.
Arthur FischbachMax Planck Institute for Biology of Ageing, Cologne, 50931, Germany.
Mikael MolinDepartment of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden.
Thomas NystromInstitute for Biomedicine, Sahlgrenska Academy, Centre for Ageing and Health - AgeCap, University of Gothenburg, Gothenburg, 405 30, Sweden. thomas.nystrom@cmb.gu.se.
University of Gothenburg · SEChalmers University of Technology · SEMax Planck Institute for Biology of Ageing · DESahlgrenska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The calcium-responsive phosphatase, calcineurin, senses changes in Ca

Indexed as

Parkinson DiseaseSaccharomyces cerevisiae ProteinsSynucleinopathiesalpha-SynucleinCalcineurinDNA-Binding ProteinsHumansProtein AggregatesSaccharomyces cerevisiaeTranscription Factorsalpha-SynucleinCalcineurinCRZ1 protein, S cerevisiaeDNA-Binding ProteinsProtein AggregatesSaccharomyces cerevisiae ProteinsTranscription FactorsCalcineurinProtein aggregationProtein phosphatase 2BProtein quality controlα-synuclein

Identifiers

PMID37620860
PMCPMC10464345
OpenAlexW4386136926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.