Evidence map›Paper›PMID 37620721›Full record

ArticleJournal of general internal medicine2023

Patient Cognitive Status and Physician Recommendations for Cardiovascular Disease Treatment: Results of Two Nationwide, Randomized Survey Studies.

Deborah A Levine, Rachael T Whitney, Andrzej T Galecki, Angela Fagerlin, Lauren P Wallner, Supriya Shore, Kenneth M Langa, Brahmajee K Nallamothu, Lewis B Morgenstern, Bruno Giordani and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Deborah A LevineDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA. deblevin@umich.edu.ORCID 0000-0002-6864-8001
Rachael T WhitneyDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA.
Andrzej T GaleckiDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA.
Angela FagerlinDepartment of Population Health Sciences, University of Utah, and Salt Lake City VA Informatics Decision-Enhancement and Analytic Sciences (IDEAS 2.0) Center for Innovation, Salt Lake City, UT, USA.
Lauren P WallnerDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA.
Supriya ShoreDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA.
Kenneth M LangaDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA.
Brahmajee K NallamothuDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA.
Lewis B MorgensternDepartment of Neurology and Stroke Program, U-M, Ann Arbor, MI, USA.
Bruno GiordaniDepartment of Psychiatry, U-M, Ann Arbor, MI, USA.
Bailey K RealeDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA.
Emilie M BlairDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA.
Anupriya SharmaDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA.
Mohammed U KabetoDepartment of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, USA.
Brenda L PlassmanDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Darin B ZahuranecDepartment of Neurology and Stroke Program, U-M, Ann Arbor, MI, USA.
University of Michigan · USDuke University · USLake Erie College of Osteopathic Medicine · USUniversity of Utah · US

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lona Mody, RAYMOND L YUNG · 2004 to 2026
$29.2M
Research Education ComponentP30AG072931 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Henry L Paulson · 2021 to 2026
$26.5M
The Effect of Lower Blood Pressure over the Life Course on Late-life Cognition in Blacks, Hispanics, and Whites (BP-COG)R01NS102715 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2017 to 2021
$3.8M
Decision Making for Cardiovascular Therapy in Adults with Mild Cognitive ImpairmentR01AG051827 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2016 to 2020
$3.6M
The Effect of Vascular Risk Factors on Risk of Alzheimer's Disease and Related Dementias after Stroke (STROKE COG)RF1AG068410 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2020 to 2020
$3.1M
NIA NIH HHS P30 AG024824NIA NIH HHS P30 AG072931NIA NIH HHS R01 AG051827NIA NIH HHS RF1 AG068410NINDS NIH HHS R01 NS102715
6 · The paper itself

Abstract

backgroundClinical guidelines recommend that older patients (65+) with mild cognitive impairment (MCI) and early-stage dementia receive similar guideline-concordant care after cardiovascular disease (CVD) events as those with normal cognition (NC). However, older patients with MCI and dementia receive less care for CVD and other conditions than those with NC. Whether physician recommendations for guideline-concordant treatments after two common CVD events, acute myocardial infarction (AMI) and acute ischemic stroke (stroke), differ between older patients with NC, MCI, and early-stage dementia is unknown.

objectiveTo test the influence of patient cognitive status (NC, MCI, early-stage dementia) on physicians' recommendations for guideline-concordant treatments for AMI and stroke.

designWe conducted two parallel, randomized survey studies for AMI and stroke in the US using clinical vignettes where the hypothetical patient's cognitive status was randomized between physicians.

participantsThe study included cardiologists, neurologists, and generalists who care for most patients hospitalized for AMI and stroke. MAIN MEASURES: The primary outcome was a composite quality score representing the number of five guideline-concordant treatments physicians recommended for a hypothetical patient after AMI or stroke. KEY

results1,031 physicians completed the study (58.5% response rate). Of 1,031 respondents, 980 physicians had complete information. After adjusting for physician factors, physicians recommended similar treatments after AMI and stroke in hypothetical patients with pre-existing MCI (adjusted ratio of expected composite quality score, 0.98 [95% CI, 0.94, 1.02]; P = 0.36) as hypothetical patients with NC. Physicians recommended fewer treatments to hypothetical patients with pre-existing early-stage dementia than to hypothetical patients with NC (adjusted ratio of expected composite quality score, 0.90 [0.86, 0.94]; P < 0.001).

conclusionIn these randomized survey studies, physicians recommended fewer guideline-concordant AMI and stroke treatments to hypothetical patients with early-stage dementia than those with NC. We did not find evidence that physicians recommend fewer treatments to hypothetical patients with MCI than those with NC.

Indexed as

Cardiovascular DiseasesDementiaIschemic StrokeMyocardial InfarctionPhysiciansStrokeCognitionHumansSurveys and Questionnairesagingalzheimer’scardiovascular diseasehealth services research

Identifiers

PMID37620721
PMCPMC10651817
OpenAlexW4386118660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.