ArticleNature chemical biology2023
Engineering co-utilization of glucose and xylose for chemical overproduction from lignocellulose.
Article in Nature chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
29 citing papers in PubMed, 89 citations in OpenAlex.
- Exploring archaeal resources for biomass-derived pentose utilization: pathways, extremozymes, and bioprocessing applications.World journal of microbiology & biotechnology · 2026Review
- Upcycling Vegetable Waste Into Functional Food Ingredients via Synergistic Microbial Engineering and Artificial Intelligence.Comprehensive reviews in food science and food safety · 2026Review
- Yeast species resource exploration and application in cell factories.Synthetic and systems biotechnology · 2026Review
- EngineeringSynthetic and systems biotechnology · 2026Article
- Comparative fermentability of a glucose/xylose enriched enzymatic slurry using different yeast strains.Bioprocess and biosystems engineering · 2026Article
- Lignocellulosic Films: Preparation, Properties, and Applications.Chemical reviews · 2025Review
- Xylose Metabolism Perturbation in Yarrowia lipolytica for Efficient Succinic Acid Bioproduction from Lignocellulosic Biomass.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A Review of the Progress in the Microbial Biosynthesis of Prenylated Aromatic Compounds.Molecules (Basel, Switzerland) · 2025Review
- Integration of metabolic and evolutionary processes to construct efficient xylose-utilizing strain ofSynthetic and systems biotechnology · 2025Article
- Engineering a modular pectin-to-lipids bioconversion system using two Kluyveromyces marxianus strains.Bioresources and bioprocessing · 2025Article
- Efficient pretreatment of Phragmites australis biomass using glutamic acid for bioethanol production by a hybrid hydrolysis and fermentation strategy.Bioprocess and biosystems engineering · 2025Article
- High-level production of free fatty acids from lignocellulose hydrolysate by co-utilizing glucose and xylose in yeast.Synthetic and systems biotechnology · 2025Article
- Economic and sustainable revolution to facilitate one-carbon biomanufacturing.Nature communications · 2025Review
- Modular deregulation of central carbon metabolism for efficient xylose utilization in Saccharomyces cerevisiae.Nature communications · 2025Article
- Regulating triacylglycerol cycling for high-efficiency production of polyunsaturated fatty acids and derivatives.Nature communications · 2025Article
- Construction of Corynebacterium glutamicum chassis for preferential utilization of xylose by adaptive laboratory evolution.Biotechnology letters · 2025Article
- Unsilencing a cryptic xylose metabolic pathway in Rhodococcus jostii RHA1 for efficient lipid production from lignocellulosic biomass.Journal of biological engineering · 2025Article
- Genome-scale CRISPRi screen identifies pcnB repression conferring improved physiology for overproduction of free fatty acids in Escherichia coli.Nature communications · 2025Article
- Engineering Xylose Isomerase and Reductase Pathways in Yarrowia lipolytica for Efficient Lipid Production.Microbial biotechnology · 2025Article
- EngineeringBiodesign research · 2025Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Bio-refining lignocellulose could provide a sustainable supply of fuels and fine chemicals; however, the challenges associated with the co-utilization of xylose and glucose typically compromise the efficiency of lignocellulose conversion. Here we engineered the industrial yeast Ogataea polymorpha (Hansenula polymorpha) for lignocellulose biorefinery by facilitating the co-utilization of glucose and xylose to optimize the production of free fatty acids (FFAs) and 3-hydroxypropionic acid (3-HP) from lignocellulose. We rewired the central metabolism for the enhanced supply of acetyl-coenzyme A and nicotinamide adenine dinucleotide phosphate hydrogen, obtaining 30.0 g l
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.