ReviewNPJ microgravity2023
Plant and microbial science and technology as cornerstones to Bioregenerative Life Support Systems in space.
Review in NPJ microgravity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 61 citations in OpenAlex.
- Hypobaric Resilience of Matrix Polysaccharide Biosynthesis in Plants.Plant direct · 2026Article
- The Potential Anaerobic Cultivation of Microbial Biomass for Astronaut Nutrition During Long-Term Space Flight.Life (Basel, Switzerland) · 2026Article
- Effects of the space environment on articular cartilage homeostasis: a review.NPJ microgravity · 2026Review
- Orbital biomanufacturing: the key to space resiliency, operational persistence, and ethical sustainability.NPJ microgravity · 2026Review
- Anabaena-a promising chassis for space exploration.NPJ microgravity · 2026Review
- Foodomics of Rice Grains in Astrobiology: Spaceflight-Induced Modulation of Aroma, Texture, and Protein Digestibility in Thai Landrace Rice (466HM) Aboard the Shijian-19 (SJ-19) Low Earth Orbit Mission.Life (Basel, Switzerland) · 2026Article
- Emerging Chemical and Biological Materials Technologies in the Extraplanetary Environment.Nano-micro letters · 2026Review
- Harnessing desiccation-tolerant cyanobacteria as biosensors for LexA-mediated responses in deep space.Frontiers in microbiology · 2026Article
- Space-flown spearmint (Frontiers in plant science · 2026Article
- Integrating resource utilization and bioregenerative life support systems for sustainable space exploration.Frontiers in microbiology · 2026Review
- Searching for extraterrestrial life advances terrestrial sustainability.Nature communications · 2025Review
- Superfood potential of Chlorella vulgaris: productivity and antioxidant boost under simulated moon and microgravity conditions.NPJ microgravity · 2025Article
- Neural changes in microgravity: Investigating the effects of aerospace environments.IBRO neuroscience reports · 2025Review
- Article
- Spaceward senses: examining retronasal aroma and mouthfeel perception in simulated space-microgravity environments.NPJ science of food · 2025Article
- Synthetic biology for space exploration.NPJ microgravity · 2025Review
- Exploring plant responses to altered gravity for advancing space agriculture.Plant communications · 2025Review
- Establishing baselines for prebiotic production in controlled environments for applications in space and vertical farming.Heliyon · 2025Article
- Developing an alternative medium for in-space biomanufacturing.Nature communications · 2025Article
- The EDEN ISS mobile test facility microbiome changes by cleaning and continued use.Frontiers in microbiomes · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 11 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Long-term human space exploration missions require environmental control and closed Life Support Systems (LSS) capable of producing and recycling resources, thus fulfilling all the essential metabolic needs for human survival in harsh space environments, both during travel and on orbital/planetary stations. This will become increasingly necessary as missions reach farther away from Earth, thereby limiting the technical and economic feasibility of resupplying resources from Earth. Further incorporation of biological elements into state-of-the-art (mostly abiotic) LSS, leading to bioregenerative LSS (BLSS), is needed for additional resource recovery, food production, and waste treatment solutions, and to enable more self-sustainable missions to the Moon and Mars. There is a whole suite of functions crucial to sustain human presence in Low Earth Orbit (LEO) and successful settlement on Moon or Mars such as environmental control, air regeneration, waste management, water supply, food production, cabin/habitat pressurization, radiation protection, energy supply, and means for transportation, communication, and recreation. In this paper, we focus on air, water and food production, and waste management, and address some aspects of radiation protection and recreation. We briefly discuss existing knowledge, highlight open gaps, and propose possible future experiments in the short-, medium-, and long-term to achieve the targets of crewed space exploration also leading to possible benefits on Earth.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.