Evidence map›Paper›PMID 37620389›Full record

ArticleNature communications2023

Downregulation of chemokine receptor 9 facilitates CD4

Keiko Ono, Tomohisa Sujino, Kentaro Miyamoto, Yosuke Harada, Satoshi Kojo, Yusuke Yoshimatsu, Shun Tanemoto, Yuzo Koda, Jiawen Zheng, Kazutoshi Sayama and 11 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Pathways and mechanisms of CD4Trends in immunology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 2 countries.

Keiko Ono *Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Tomohisa SujinoCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan. tsujino1224@keio.jp.ORCID http://orcid.org/0000-0003-0699-6577
Kentaro Miyamoto *Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Yosuke Harada *Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Satoshi KojoLaboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.ORCID http://orcid.org/0000-0002-9263-8831
Yusuke YoshimatsuDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Shun TanemotoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Yuzo KodaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0001-6009-4043
Jiawen ZhengLaboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Kazutoshi SayamaApplied Life Science Course, College of Agriculture, Shizuoka University, Shizuoka, Japan.
Tsuyoshi KoideMouse Genomics Resource Laboratory, National Institute of Genetics, Shizuoka, Japan.ORCID http://orcid.org/0000-0002-1055-9073
Toshiaki TerataniDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Yohei MikamiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0001-5104-4415
Kaoru TakabayashiCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan.
Nobuhiro NakamotoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0001-5203-7444
Naoki HosoeCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan.
Mariya LondonLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, 10065, USA.
Haruhiko OgataCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan.
Daniel MucidaLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, 10065, USA.ORCID http://orcid.org/0000-0002-0000-0452
Ichiro TaniuchiLaboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.ORCID http://orcid.org/0000-0002-9853-9068
Takanori KanaiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. takagast@keio.jp.
Keio University · JPRIKEN Center for Integrative Medical Sciences · JPHoward Hughes Medical Institute · USKanazawa University · JPNational Institute of Genetics · JPRockefeller University · USShizuoka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal intraepithelial lymphocytes (IELs) reside in the gut epithelial layer, where they help in maintaining intestinal homeostasis. Peripheral CD4

Indexed as

Intraepithelial LymphocytesReceptors, CCRAnimalsCell DifferentiationDown-RegulationEpitheliumMiceUp-RegulationCC chemokine receptor 9Receptors, CCR

Identifiers

PMID37620389
PMCPMC10449822
OpenAlexW4386121027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.