ArticleScientific reports2023
Spatiotemporal patterns of spontaneous movement in neonates are significantly linked to risk of autism spectrum disorders at 18 months old.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- Early Detection Methods for Autism Spectrum Disorder: From Clinical Screening to Multimodal AI.Diagnostics (Basel, Switzerland) · 2026Review
- Exploring autism spectrum profiles via network analysis of parent-reported ASSQ patterns.BMC psychiatry · 2026Article
- Naturalistic facial dynamics enable quantitative clinical assessment of atypical expression phenotypes in children with autism spectrum disorder.NPJ digital medicine · 2026Article
- Manual and automated assessments of general movements in neonates are associated with early autism risk at 18 months.Scientific reports · 2026Article
- A systematic review of portable technologies for the early assessment of motor development in infants.NPJ digital medicine · 2025Article
- Marker-Less Video Analysis of Infant Movements for Early Identification of Neurodevelopmental Disorders.Diagnostics (Basel, Switzerland) · 2025Article
- Sensory-movement underpinnings of lifelong neurodivergence: getting a grip on autism.Frontiers in integrative neuroscience · 2025Article
- Risk of autism spectrum disorder at 18 months of age is associated with prenatal level of polychlorinated biphenyls exposure in a Japanese birth cohort.Scientific reports · 2024Article
- Second phase Chiba study of mother and child health (C-MACH): Japanese birth cohort study with multiomics analyses.BMJ open · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infants make spontaneous movements from the prenatal period. Several studies indicate that an atypical pattern of body motion during infancy could be utilized as an early biomarker of autism spectrum disorders (ASD). However, to date, little is known about whether the body motion pattern in neonates is associated with ASD risk. The present study sought to clarify this point by examining, in a longitudinal design, the link between features of spontaneous movement at about two days after birth and ASD risk evaluated using the Modified Checklist for Autism in Toddlers by their caregivers at 18 months old. The body movement features were quantified by a recently developed markerless system of infant body motion analysis. Logistic regression analysis revealed that ASD risk at 18 months old is associated with the pattern of spontaneous movement at the neonatal stage. Further, logistic regression based on body movement features during sleep shows better performance in classifying high- and low-risk infants than during the awake state. These findings raise the possibility that early signs of ASD risk may emerge at a developmental stage far earlier than previously thought.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.