Evidence map›Paper›PMID 37620338›Full record

ArticleScientific reports2023

Iridocorneal angle imaging of a human donor eye by spectral-domain optical coherence tomography.

Shangbang Luo, Guy Holland, Reza Khazaeinezhad, Samantha Bradford, Rohan Joshi, Tibor Juhasz

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shangbang LuoDepartment of Biomedical Engineering, University of California, Irvine, Irvine, CA, 92697, USA.
Guy HollandViaLase Inc., Aliso Viejo, CA, 92656, USA.
Reza KhazaeinezhadViaLase Inc., Aliso Viejo, CA, 92656, USA.
Samantha BradfordDepartment of Ophthalmology, University of California, Irvine, Irvine, CA, 92697, USA.
Rohan JoshiDepartment of Biomedical Engineering, University of California, Irvine, Irvine, CA, 92697, USA.
Tibor JuhaszDepartment of Biomedical Engineering, University of California, Irvine, Irvine, CA, 92697, USA. tjuhasz@hs.uci.edu.

Funding

NEI UCI Center Core Grant for Vision ResearchP30EY034070 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Rachel Wagner Martin · 2022 to 2026
$3.7M
Non-Invasive Femtosecond Laser Glaucoma Surgery Guided by Micron-Resolution OCTR01EY030304 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI JUHASZ, TIBOR · 2019 to 2022
$1.9M
NEI NIH HHS P30 EY034070NEI NIH HHS R01 EY030304
6 · The paper itself

Abstract

Iridocorneal angle (ICA) details particularly the trabecular meshwork (TM), Schlemm's canal (SC), and collector channels (CCs) play crucial roles in the regulation of the aqueous outflow in the eyes and are closely associated with glaucoma. Current clinical gonioscopy imaging provides no depth information, and studies of 3D high-resolution optical coherence tomography (OCT) imaging of these structures are limited. We developed a custom-built spectral-domain (SD-) OCT imaging system to fully characterize the angle details. Imaging of a human cadaver eye reveals the visibility of details in the TM/SC/CC region via a 'crossline' scanning and a series of image processing. This shows that ICA imaging can be used for preoperative glaucoma inspections in the clinical setting with the proposed prototype.

Indexed as

GlaucomaTomography, Optical CoherenceHumansImage Processing, Computer-AssistedTissue DonorsTrabecular Meshwork

Identifiers

PMID37620338
PMCPMC10449890

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.