Evidence map›Paper›PMID 37619815›Full record

ArticleOphthalmology. Glaucoma

Assessment of Remote Training, At-Home Testing, and Test-Retest Variability of a Novel Test for Clustered Virtual Reality Perimetry.

Zer Keen Chia, Alan W Kong, Marcus L Turner, Murtaza Saifee, Bertil E Damato, Benjamin T Backus, James J Blaha, Joel S Schuman, Michael S Deiner, Yvonne Ou

Open access · hybridAbstract read
In one paragraph

Article in Ophthalmology. Glaucoma. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Portable perimetry devices for glaucoma patients -practicality in daily clinical practice and glaucoma expert assessment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
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  12. Pilot study comparing a new virtual reality-based visual field test to standard perimetry in children.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2024
    Article
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  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zer Keen ChiaDepartment of Ophthalmology, UCSF School of Medicine, San Francisco, California.
Alan W KongDepartment of Ophthalmology, UCSF School of Medicine, San Francisco, California.
Marcus L TurnerDepartment of Ophthalmology, UCSF School of Medicine, San Francisco, California.
Murtaza SaifeeDepartment of Ophthalmology, UCSF School of Medicine, San Francisco, California.
Bertil E DamatoDepartment of Ophthalmology, UCSF School of Medicine, San Francisco, California.
Benjamin T BackusVivid Vision, Inc., San Francisco, California.
James J BlahaVivid Vision, Inc., San Francisco, California.
Joel S SchumanGlaucoma Service, Wills Eye Hospital, Philadelphia, Pennsylvania; Vickie and Jack Farber Vision Research Center, Wills Eye Hospital, Philadelphia, Pennsylvania; Department of Ophthalmology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania; Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania.
Michael S DeinerDepartment of Ophthalmology, UCSF School of Medicine, San Francisco, California.
Yvonne OuDepartment of Ophthalmology, UCSF School of Medicine, San Francisco, California. Electronic address: yvonne.ou@ucsf.edu.
University of California, San Francisco · USDuke University · US

Funding

Clustered home assessment of visual fields in patients with glaucomaR44EY035203 · NEI · VIVID VISION, INC. · PI BACKUS, BENJAMIN T · 2023 to 2024
$1.6M
NEI NIH HHS R44 EY035203
6 · The paper itself

Abstract

objectiveTo assess the feasibility of remotely training glaucoma patients to take a 10-session clustered virtual reality (VR) visual field (VF) test (Vivid Vision Perimetry [VVP-10]) at home, analyze results for test-retest variability, and assess correspondence with conventional perimetry.

designCross-sectional study. SUBJECTS: Twenty-one subjects with glaucoma were enrolled and included in the feasibility assessment of remote training. Thirty-six eyes were used for test-retest analysis and determination of concordance with the Humphrey Field Analyzer (HFA).

methodsSubjects were provided with a mobile VR headset containing the VVP-10 test software and trained remotely via video conferencing. Subjects were instructed to complete 10 sessions over a 14-day period.

main outcome measuresFeasibility was determined by the number of subjects who were able to independently complete VVP-10 over the 14-day period after 1 remote training session. The intraclass correlation coefficient (ICC) for average fraction seen across 10 sessions and the standard error (SE) of the mean were primary outcome measures for assessing test-retest variability. Correlation with HFA mean sensitivity (MS) across eyes, was a secondary outcome measure.

resultsTwenty subjects (95%) successfully completed the VVP-10 test series after 1 training session. The ICC for VVP-10 was 0.95 (95% confidence interval [CI], 0.92-0.97). The mean SE in units of fraction seen was 0.012. The Spearman correlations between VVP-10 average fraction seen and HFA MS were 0.87 (95% CI, 0.66-0.98) for moderate-to-advanced glaucoma eyes, and decreased to 0.67 (95% CI, 0.28-0.94) when all eyes were included.

conclusionsRemote training of patients at home is feasible, and subsequent remote clustered VF testing using VVP-10 by patients on their own, without any further interactions with caregivers or study staff, was possible. At-home VVP-10 results demonstrated low test-retest variability. Future studies must be conducted to determine if VVP-10, taken at home as convenient for the patient, may be a viable supplement to provide equivalent or complementary results to that of standard in-clinic assessment of visual function in glaucoma. FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Indexed as

GlaucomaVisual Field TestsCross-Sectional StudiesHumansVision DisordersVisual FieldsClustered visual field testingFeasibilityGlaucomaRemote trainingVirtual realityVisual field testing

Identifiers

PMID37619815
PMCPMC13217229
OpenAlexW4386082898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.