Evidence map›Paper›PMID 37616319›Full record

ArticlePloS one2023

Is scientific evidence enough? Using expert opinion to fill gaps in data in antimicrobial resistance research.

Melanie Cousins, E Jane Parmley, Amy L Greer, Elena Neiterman, Irene A Lambraki, Tiscar Graells, Anaïs Léger, Patrik J G Henriksson, Max Troell, Didier Wernli and 3 more

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Melanie CousinsSchool of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.ORCID 0000-0003-3725-4058
E Jane ParmleyDepartment of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
Amy L GreerDepartment of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
Elena NeitermanSchool of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.
Irene A LambrakiSchool of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.
Tiscar GraellsGlobal Economic Dynamics and the Biosphere, Royal Swedish Academy of Sciences, Stockholm, Sweden.ORCID 0000-0002-2376-3559
Anaïs LégerGlobal Studies Institute, University of Geneva, Geneva, Switzerland.
Patrik J G HenrikssonStockholm Resilience Centre, Stockholm University, Stockholm, Sweden.
Max TroellStockholm Resilience Centre, Stockholm University, Stockholm, Sweden.
Didier WernliGlobal Studies Institute, University of Geneva, Geneva, Switzerland.
Peter Søgaard JørgensenGlobal Economic Dynamics and the Biosphere, Royal Swedish Academy of Sciences, Stockholm, Sweden.
Carolee A CarsonFoodborne Disease and Antimicrobial Resistance Surveillance Division, Centre for Foodborne, Environmental and Zoonotic Infectious Diseases, Public Health Agency of Canada, Guelph, Ontario, Canada.
Shannon E MajowiczSchool of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntimicrobial Resistance (AMR) is a global problem with large health and economic consequences. Current gaps in quantitative data are a major limitation for creating models intended to simulate the drivers of AMR. As an intermediate step, expert knowledge and opinion could be utilized to fill gaps in knowledge for areas of the system where quantitative data does not yet exist or are hard to quantify. Therefore, the objective of this study was to identify quantifiable data about the current state of the factors that drive AMR and the strengths and directions of relationships between the factors from statements made by a group of experts from the One Health system that drives AMR development and transmission in a European context.

methodsThis study builds upon previous work that developed a causal loop diagram of AMR using input from two workshops conducted in 2019 in Sweden with experts within the European food system context. A secondary analysis of the workshop transcripts was conducted to identify semi-quantitative data to parameterize drivers in a model of AMR. MAIN

findingsParticipants spoke about AMR by combining their personal experiences with professional expertise within their fields. The analysis of participants' statements provided semi-quantitative data that can help inform a future of AMR emergence and transmission based on a causal loop diagram of AMR in a Swedish One Health system context.

conclusionUsing transcripts of a workshop including participants with diverse expertise across the system that drives AMR, we gained invaluable insight into the past, current, and potential future states of the major drivers of AMR, particularly where quantitative data are lacking.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialHumansKnowledgeMedical AssistanceAnti-Bacterial Agents

Identifiers

PMID37616319
PMCPMC10449168

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.