Evidence map›Paper›PMID 37615573›Full record

ArticleInternational journal of cancer2024

Age at diagnosis for lung, colon, breast and prostate cancers: An international comparative study.

Hana Zahed, Xiaoshuang Feng, Mahdi Sheikh, Freddie Bray, Jacques Ferlay, Ophira Ginsburg, Meredith S Shiels, Hilary A Robbins

Open access · hybridAbstract read
In one paragraph

Article in International journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Sexual health of patients with lung cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Lectin fromACS omega · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Hana ZahedGenomic Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-5731-8859
Xiaoshuang FengGenomic Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-7933-3996
Mahdi SheikhGenomic Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.
Freddie BrayCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.
Jacques FerlayCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.
Ophira GinsburgCenter for Global Health, National Cancer Institute, Rockville, Maryland, USA.
Meredith S ShielsInfections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.ORCID 0000-0001-8390-6091
Hilary A RobbinsGenomic Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-6041-6866
Centre international de recherche sur le cancer · FRCenter for Global Health · USNational Cancer Institute · US

Funding

Infections, immunity, and inflammation in cancerZIACP010150 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ENGELS, ERIC A · 2009 to 2025
$24.0M
Translating Molecular and Clinical Data to Population Lung Cancer Risk AssessmentU19CA203654 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Christopher I. Amos · 2017 to 2026
$23.7M
The Lung EArly Proteins project: A LEAP toward implementing biomarkers in lung cancer screeningR01CA262164 · NCI · INTERNATIONAL AGENCY FOR RES ON CANCER · PI ROBBINS, HILARY A. · 2022 to 2025
$2.0M
Evaluating risk prediction models for use in lung cancer screening in diverse populations around the worldR03CA245979 · NCI · INTERNATIONAL AGENCY FOR RES ON CANCER · PI ROBBINS, HILARY A. · 2020 to 2020
$112k
NCI NIH HHS R01 CA262164NCI NIH HHS R03 CA245979NCI NIH HHS U19 CA203654World Health Organization 001
6 · The paper itself

Abstract

Differences in the average age at cancer diagnosis are observed across countries. We therefore aimed to assess international variation in the median age at diagnosis of common cancers worldwide, after adjusting for differences in population age structure. We used IARC's Cancer Incidence in Five Continents (CI5) Volume XI database, comprising cancer diagnoses between 2008 and 2012 from population-based cancer registries in 65 countries. We calculated crude median ages at diagnosis for lung, colon, breast and prostate cancers in each country, then adjusted for population age differences using indirect standardization. We showed that median ages at diagnosis changed by up to 10 years after standardization, typically increasing in low- and middle-income countries (LMICs) and decreasing in high-income countries (HICs), given relatively younger and older populations, respectively. After standardization, the range of ages at diagnosis was 12 years for lung cancer (median age 61-Bulgaria vs 73-Bahrain), 12 years for colon cancer (60-the Islamic Republic of Iran vs 72-Peru), 10 years for female breast cancer (49-Algeria, the Islamic Republic of Iran, Republic of Korea vs 59-USA and others) and 10 years for prostate cancer (65-USA, Lithuania vs 75-Philippines). Compared to HICs, populations in LMICs were diagnosed with colon cancer at younger ages but with prostate cancer at older ages (both p

Indexed as

Breast NeoplasmsColonic NeoplasmsLung NeoplasmsProstatic NeoplasmsHumansIncidenceLungMaleMiddle Agedage at cancer diagnosiscancer epidemiologyinternational comparison

Identifiers

PMID37615573
PMCPMC11153845
OpenAlexW4386116069

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.