Evidence map›Paper›PMID 37615438›Full record

ArticleMicrobiology spectrum2023

The interplay between Epstein-Barr virus DNA and gut microbiota in the development of arthritis in a mouse model.

Sukayna Fadlallah, Elio R Bitar, Hadi Hussein, Mary-Ann Jallad, Ghassan M Matar, Elias A Rahal

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sukayna FadlallahDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut , Beirut, Lebanon.
Elio R BitarDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut , Beirut, Lebanon.
Hadi HusseinDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut , Beirut, Lebanon.
Mary-Ann JalladDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut , Beirut, Lebanon.
Ghassan M MatarDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut , Beirut, Lebanon.
Elias A RahalDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut , Beirut, Lebanon.ORCID 0000-0002-1096-7042
American University of Beirut · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceEpstein-Barr virus (EBV) DNA alters the composition and diversity of the gut microbiota in a rheumatoid arthritis (RA) mouse model. These induced changes are associated with enhanced severity of symptoms. This better understanding of the various factors involved in the development of RA will possibly help in creating individualized treatments for RA patients including target mediators triggered by viral DNA. Given that a large swathe of the population harbors EBV, a significant proportion of subjects with arthritis may benefit from possible approaches that target EBV or mediators triggered by this virus.

Indexed as

C57BL/6J miceEpstein-Barr virus DNAgut microbiotaproinflammatory responsesrheumatoid arthritis

Identifiers

PMID37615438
PMCPMC10581075
OpenAlexW4386117313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.