Evidence map›Paper›PMID 37614813›Full record

ArticleRespirology case reports2023

Endobronchial metastasis of hepatocellular carcinoma treated with Lenvatinib: A case report.

Shota Takei, Akihiro Yoshimura, Chie Yamamoto, Seita Kataoka, Nobutaka Kataoka, Kenji Morimoto, Masahiro Iwasaku, Shinsaku Tokuda, Tadaaki Yamada, Takayuki Takeda and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 68% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 0 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Shota TakeiDepartment of Pulmonary Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Akihiro YoshimuraDepartment of Pulmonary Medicine Kyoto Prefectural University of Medicine Kyoto Japan.ORCID https://orcid.org/0000-0002-3753-2110
Chie YamamotoDepartment of Infectious Disease Kyoto Prefectural University of Medicine Kyoto Japan.
Seita KataokaDepartment of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine Kyoto Japan.
Nobutaka KataokaDepartment of Pulmonary Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Kenji MorimotoDepartment of Pulmonary Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Masahiro IwasakuDepartment of Pulmonary Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Shinsaku TokudaDepartment of Pulmonary Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Tadaaki YamadaDepartment of Pulmonary Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Takayuki TakedaDepartment of Respiratory Medicine Japanese Red Cross Kyoto Daini Hospital Kyoto Japan.ORCID https://orcid.org/0000-0002-8375-6940
Koichi TakayamaDepartment of Pulmonary Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Kyoto Prefectural University of Medicine · JPJapanese Red Cross Society Kyoto Daini Hospital · JPKyoto Prefectural University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endobronchial metastasis (EBM) of hepatocellular carcinoma (HCC) is rare though HCC often metastasizes to the lungs. In this case report, a 74-year-old man with a history of HCC with chronic hepatitis C experienced hemoptysis and a dry cough. During immunotherapy for postoperative recurrent HCC, chest computed tomography (CT) revealed soft tissue shadows in the right upper and lower lobe bronchi, and we pathologically diagnosed as EBM of HCC using bronchoscopy. Although the prognosis of HCC with EBM is poor, lenvatinib, a tyrosine kinase inhibitor, was administered and resulted in improved symptoms, decreased tumour markers, and reduced EBM shadows on chest CT scans. To the best of our knowledge, this is the first case of lenvatinib monotherapy for EBM of HCC. It is important to perform a bronchoscopy for early diagnosis of EBM, followed by lenvatinib treatment.

Indexed as

bronchoscopyendobronchial metastasishepatocellular carcinomalenvatinib

Identifiers

PMID37614813
PMCPMC10442773
OpenAlexW4386069341

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.