Evidence map›Paper›PMID 37614745›Full record

ReviewFrontiers in nutrition2023

Current knowledges in pharmaconutrition: "

Nicola Cecchi, Roberta Romanelli, Flavia Ricevuti, Marianna Amitrano, Maria Grazia Carbone, Michele Dinardo, Ernesto Burgio

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nicola CecchiClinical Nutrition Unit - A.O.R.N. Santobono-Pausilipon Children's Hospital, Naples, Italy.
Roberta RomanelliClinical Nutrition Unit - A.O.R.N. Santobono-Pausilipon Children's Hospital, Naples, Italy.
Flavia RicevutiClinical Nutrition Unit - A.O.R.N. Santobono-Pausilipon Children's Hospital, Naples, Italy.
Marianna AmitranoDepartment of Translational Medical Science, Section of Pediatrics, University of Naples "Federico II", Naples, Italy.
Maria Grazia CarboneClinical Nutrition Unit - A.O.R.N. Santobono-Pausilipon Children's Hospital, Naples, Italy.
Michele DinardoClinical Nutrition Unit - A.O.R.N. Santobono-Pausilipon Children's Hospital, Naples, Italy.
Ernesto BurgioECERI-European Cancer and Environment Research Institute, Brussels, Belgium.
Santobono Children's Hospital · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain tumors account for 20-25% of pediatric cancers. The most frequent type of brain tumor is Glioma from grade I to grade IV according to the rate of malignancy. Current treatments for gliomas use chemotherapy, radiotherapy, tyrosine kinase inhibitors, monoclonal antibodies and surgery, but each of the treatment strategies has several serious side effects. Therefore, to improve treatment efficacy, it is necessary to tailor therapies to patient and tumor characteristics, using appropriate molecular targets. An increasingly popular strategy is pharmaconutrition, which combines a tailored pharmacological treatment with a diet designed to synergize the effects of drugs. In this review we deal in the molecular mechanisms, the epigenetic effects and modulation of the oxidative stress pathway of ketogenic diets, that underlie its possible role, in the treatment of infantile gliomas, as a complementary approach to conventional cancer therapy.

Indexed as

brain cancerepigeneticgliomaketogenic dietpediatrics

Identifiers

PMID37614745
PMCPMC10442509
OpenAlexW4385660808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.