Evidence map›Paper›PMID 37614678›Full record

ArticleBiomicrofluidics2023

Artificial intelligence-driven electrochemical immunosensing biochips in multi-component detection.

Yuliang Zhao, Xiaoai Wang, Tingting Sun, Peng Shan, Zhikun Zhan, Zhongpeng Zhao, Yongqiang Jiang, Mingyue Qu, Qingyu Lv, Ying Wang and 2 more

Abstract read
In one paragraph

Article in Biomicrofluidics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuliang ZhaoSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066000, Hebei, China.ORCID https://orcid.org/0000-0002-4519-7404
Xiaoai WangSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066000, Hebei, China.ORCID https://orcid.org/0000-0001-9369-6884
Tingting SunSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066000, Hebei, China.ORCID https://orcid.org/0009-0005-9189-3530
Peng ShanSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066000, Hebei, China.ORCID https://orcid.org/0000-0002-3274-3226
Zhikun ZhanSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066000, Hebei, China.
Zhongpeng ZhaoState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.
Yongqiang JiangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.
Mingyue QuThe PLA Rocket Force Characteristic Medical Center, Beijing 100088, China.ORCID https://orcid.org/0000-0001-9967-1573
Qingyu LvState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.
Ying WangSchool of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China.
Peng LiuState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.ORCID https://orcid.org/0000-0001-9948-0259
Shaolong ChenState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.ORCID https://orcid.org/0009-0001-4734-2169

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrochemical Immunosensing (EI) combines electrochemical analysis and immunology principles and is characterized by its simplicity, rapid detection, high sensitivity, and specificity. EI has become an important approach in various fields, such as clinical diagnosis, disease prevention and treatment, environmental monitoring, and food safety. However, EI multi-component detection still faces two major bottlenecks: first, the lack of cost-effective and portable detection platforms; second, the difficulty in eliminating batch differences and accurately decoupling signals from multiple analytes. With the gradual maturation of biochip technology, high-throughput analysis and portable detection utilizing the advantages of miniaturized chips, high sensitivity, and low cost have become possible. Meanwhile, Artificial Intelligence (AI) enables accurate decoupling of signals and enhances the sensitivity and specificity of multi-component detection. We believe that by evaluating and analyzing the characteristics, benefits, and linkages of EI, biochip, and AI technologies, we may considerably accelerate the development of EI multi-component detection. Therefore, we propose three specific prospects: first, AI can enhance and optimize the performance of the EI biochips, addressing the issue of multi-component detection for portable platforms. Second, the AI-enhanced EI biochips can be widely applied in home care, medical healthcare, and other areas. Third, the cross-fusion and innovation of EI, biochip, and AI technologies will effectively solve key bottlenecks in biochip detection, promoting interdisciplinary development. However, challenges may arise from AI algorithms that are difficult to explain and limited data access. Nevertheless, we believe that with technological advances and further research, there will be more methods and technologies to overcome these challenges.

Identifiers

PMID37614678
PMCPMC10444200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.