ArticleACS catalysis2023
Mechanism of Cu-Catalyzed Iododeboronation: A Description of Ligand-Enabled Transmetalation, Disproportionation, and Turnover in Cu-Mediated Oxidative Coupling Reactions.
Article in ACS catalysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Photochemical Reaction Discovery Enabled by the Dynamic Speciation of Copper Complexes.Angewandte Chemie (International ed. in English) · 2026Article
- High-Yield Room-Temperature ArylACS organic & inorganic Au · 2026Article
- Graph-Based Internal Coordinate Analysis for Transition State Characterization.Journal of chemical theory and computation · 2026Article
- Article
- Copper-catalyzed direct regioselective C5-H alkylation reactions of functionalized indoles with α-diazomalonates.Chemical science · 2025Article
- Ligand-Enabled Copper-Mediated Radioiodination of Arenes.Organic letters · 2024Article
- An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.Journal of the American Chemical Society · 2023Article
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Authors and funding
6 authors.
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Abstract
We report a combined experimental and computational study of the mechanism of the Cu-catalyzed arylboronic acid iododeboronation reaction. A combination of structural and density functional theory (DFT) analyses has allowed determination of the identity of the reaction precatalyst with insight into each step of the catalytic cycle. Key findings include a rationale for ligand (phen) stoichiometry related to key turnover events-the ligand facilitates transmetalation via H-bonding to an organoboron boronate generated in situ and phen loss/gain is integral to the key oxidative events. These data provide a framework for understanding ligand effects on these key mechanistic processes, which underpin several classes of Cu-mediated oxidative coupling reactions.
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