ReviewExperimental and therapeutic medicine2023
Negative pressure pulmonary edema (Review).
Review in Experimental and therapeutic medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Negative-pressure pulmonary edema.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Article
- Article
- Article
- Case Report: Bronchoscopy-associated negative-pressure pulmonary edema in a child with severeFrontiers in pediatrics · 2026Article
- Flash pulmonary edema caused by paroxysmal supraventricular tachycardia in a patient with preserved ejection fraction.BMC cardiovascular disorders · 2025Article
- Review
- Inspiratory effort increases blood volume in the thoracic cavity and decreases end-expiratory lung impedance: a preliminary prospective study.European journal of applied physiology · 2025Article
- Negative pressure pulmonary edema and hemorrhage after near fatal suffocation in an infant: a case report.Italian journal of pediatrics · 2025Article
- Negative pressure pulmonary edema resulting from upper airway obstruction during the post-anesthesia recovery period: a case series and literature review.BMC anesthesiology · 2025Review
- Unexpected negative-pressure pulmonary edema after tracheostomy: two case reports.JA clinical reports · 2025Article
- Case Report: VV-ECMO as a bridge to recovery from ACE inhibitor induced post-obstructive negative pressure pulmonary edema.Frontiers in medicine · 2025Article
- Severe postoperative negative pressure pulmonary edema: a case report.BMC anesthesiology · 2024Article
- Article
- Article
- Negative pressure plmonary oedema after adenotonsillectom: a case report and litrature review.Annals of medicine and surgery (2012) · 2024Article
- Negative pressure pulmonary edema: a case report and literature review.Frontiers in medicine · 2024Article
- Important functions and molecular mechanisms of aquaporins family on respiratory diseases: potential translational values.Journal of Cancer · 2024Review
- Severe hypoxemia after extubation secondary to myxedema coma: a case report.The Journal of international medical research · 2023Article
- A Case of Pulmonary Edema Due to Pentobarbital Poisoning.Journal of emergencies, trauma, and shockArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Negative pressure pulmonary edema (NPPE) is a complication resulting from acute or chronic upper airway obstruction, often posing challenges in recognition and diagnosis for clinicians. If left untreated, NPPE can lead to hypoxemia, heart failure and even shock. Furthermore, the drug treatment of NPPE remains a subject of controversy. The primary pathophysiological mechanism of NPPE involves the need for high inspiratory pressure to counteract upper airway obstruction, subsequently causing a progressive rise in negative pressure within the pleural cavity. Consequently, this results in increased pulmonary microvascular pressure, leading to the infiltration of pulmonary capillary fluid into the alveoli. NPPE exhibits numerous risk factors and causes, with laryngospasm following anesthesia and extubation being the most prevalent. The diagnosis of NPPE often presents challenges due to confusion with conditions such as gastroesophageal reflux or cardiogenic pulmonary edema, given the similarity in initial factors triggering both diseases. Upper airway patency, positive pressure non-invasive ventilation, supplemental oxygen and re-intubation mechanical ventilation are the foundation of the treatment of NPPE. The present review aims to discuss the etiology, clinical presentation, pathophysiology and management of NPPE.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.