Evidence map›Paper›PMID 37614415›Full record

ArticleAdvances in neural information processing systems2022

Local Spatiotemporal Representation Learning for Longitudinally-consistent Neuroimage Analysis.

Mengwei Ren, Neel Dey, Martin A Styner, Kelly N Botteron, Guido Gerig

Abstract read
In one paragraph

Article in Advances in neural information processing systems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Learning General-Purpose Biomedical Volume Representations using Randomized Synthesis.... International Conference on Learning Representations · 2025
    Article
  3. Learning-based inference of longitudinal image changes: Applications in embryo development, wound healing, and aging brain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Consistency Regularization Improves Placenta Segmentation in Fetal EPI MRI Time Series.Perinatal, preterm and paediatric image analysis (2025) · 2025
    Article
  5. Article
  6. Article
  7. Modeling Longitudinal Optical Coherence Tomography Images for Monitoring and Analysis of Glaucoma Progression.Shape in medical imaging : International Workshop, ShapeMI 2023, held in conjunction with MICCAI 2023, Vancouver, BC, Canada, October 8, 2023, Proceedings. ShapeMI (Workshop) (2023 : Vancouver, B.C.) · 2023
    Article
  8. ContraReg: Contrastive Learning of Multi-modality Unsupervised Deformable Image Registration.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mengwei RenNew York University.
Neel DeyNew York University.
Martin A StynerUNC-Chapel Hill.
Kelly N BotteronWUSTL School of Medicine.
Guido GerigNew York University.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5M
Cellular and molecular mechanisms governing cortical surface area overgrowth in iPSC-derived neural cells from longitudinally characterized individuals with autismR01HD055741 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph Piven · 2007 to 2026
$52.6M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
MRI-Based Presymptomatic Prediction of ASD, and Early Infant to School-Age Brain-Behavior Trajectories, Mechanisms, and Related OutcomesR01MH118362 · NIMH · WASHINGTON UNIVERSITY · PI John R Pruett · 2019 to 2026
$16.3M
A Longitudinal MRI Study Characterizing Very Early Brain Development in Infants with Down SyndromeR01HD088125 · NICHD · WASHINGTON UNIVERSITY · PI MARRUS, NATASHA · 2018 to 2024
$13.9M
Preclinical CoreP50HD103573 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GABRIEL S DICHTER · 2020 to 2026
$9.7M
THE XNAT IMAGING INFORMATICS PLATFORMR01EB009352 · NIBIB · WASHINGTON UNIVERSITY · PI Daniel Scott Marcus · 2009 to 2026
$9.3M
Preclinical CoreU54HD079124 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LI, YUN · 2013 to 2019
$8.0M
Examining Prenatal Inflammation and Neurodevelopment in a Longitudinal Fetal-to-Age 9 Imaging Study - Administrative SupplementR01MH122447 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI THOMASON, MORIAH E, TRENTACOSTA, CHRISTOPHER J · 2020 to 2025
$3.9M
A Longitudinal MRI Study of Brain Development in Fragile X SyndromeR01HD059854 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HAZLETT, HEATHER CODY · 2009 to 2014
$2.9M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276NIA NIH HHS R01 AG043434NIBIB NIH HHS R01 EB009352NICHD NIH HHS P50 HD103573NICHD NIH HHS R01 HD055741NICHD NIH HHS R01 HD059854NICHD NIH HHS R01 HD088125NICHD NIH HHS U54 HD079124NIEHS NIH HHS R01 ES032294NIMH NIH HHS R01 MH118362NIMH NIH HHS R01 MH122447
6 · The paper itself

Abstract

Recent self-supervised advances in medical computer vision exploit the global and local anatomical self-similarity for pretraining prior to downstream tasks such as segmentation. However, current methods assume i.i.d. image acquisition, which is invalid in clinical study designs where follow-up longitudinal scans track subject-specific temporal changes. Further, existing self-supervised methods for medically-relevant image-to-image architectures exploit only spatial or temporal self-similarity and do so via a loss applied only at a single image-scale, with naive multi-scale spatiotemporal extensions collapsing to degenerate solutions. To these ends, this paper makes two contributions: (1) It presents a local and multi-scale spatiotemporal representation learning method for image-to-image architectures trained on longitudinal images. It exploits the spatiotemporal self-similarity of learned multi-scale intra-subject image features for pretraining and develops several feature-wise regularizations that avoid degenerate representations; (2) During finetuning, it proposes a surprisingly simple self-supervised segmentation consistency regularization to exploit intra-subject correlation. Benchmarked across various segmentation tasks, the proposed framework outperforms both well-tuned randomly-initialized baselines and current self-supervised techniques designed for both i.i.d. and longitudinal datasets. These improvements are demonstrated across both longitudinal neurodegenerative adult MRI and developing infant brain MRI and yield both higher performance and longitudinal consistency.

Identifiers

PMID37614415
PMCPMC10445502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.