Evidence map›Paper›PMID 37614045›Full record

SynthesisInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2026

Single-stage endovascular treatment in aneurysmal subarachnoid haemorrhage with multiple intracranial aneurysms: Systematic review of the literature and multicentric retrospective experience.

Stefano Molinaro, Francesco Mistretta, Mariangela Piano, Matteo Fantoni, Simone Comelli, Ivan Gallesio, Andrea Boghi, Giuseppina Sanfilippo, Fabrizio Venturi, Paolo Remida and 2 more

Abstract readSystematic ReviewMulticenter Study
In one paragraph

Synthesis in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 2 countries.

Stefano MolinaroAzienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Interventional Neuroradiology, Torino, Piemonte, Italy.ORCID 0000-0002-7352-3107
Francesco MistrettaAzienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Interventional Neuroradiology, Torino, Piemonte, Italy.ORCID 0000-0001-5674-0575
Mariangela PianoASST Grande Ospedale Metropolitano Niguarda, Neuroradiology, Milano, Italy.
Matteo FantoniHopital Lariboisiere, Neuroradiology, Paris, Île-de-France, France.
Simone ComelliAzienda Ospedaliera Brotzu, Interventional Radiology and Neuroradiology, Cagliari, Italy.
Ivan GallesioAzienda Ospedaliera Nazionale SS Antonio e Biagio e C Arrigo, Radiology, Alessandria, Piemonte, Italy.
Andrea BoghiOspedale San Giovanni Bosco, Interventional Radiology and Neuroradiology, Torino, Piemonte, Italy.ORCID 0000-0003-1729-4036
Giuseppina SanfilippoFondazione IRCCS Policlinico San Matteo, Interventional Neuroradiology Unit, Pavia, Lombardia, Italy.
Fabrizio VenturiOspedale Santa Croce, Neuroradiology, Cuneo, Piemonte, Italy.
Paolo RemidaOspedale San Gerardo, Neuroradiology, Monza, Lombardia, Italy.
Riccardo RussoAzienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Interventional Neuroradiology, Torino, Piemonte, Italy.ORCID 0000-0002-9091-7394
Mauro BerguiUniversity of Turin, Neuroradiology, Torino, Piemonte, Italy.
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Ospedaliera G. Brotzu · ITAzienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo · ITAzienda Ospedaliera San Gerardo · ITAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITHôpital Lariboisière · FROspedale San Giovanni Bosco · ITPoliclinico San Matteo Fondazione · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesThe presence of multiple intracranial aneurysms in patients with acute subarachnoid haemorrhage is a condition with no evidence of optimal treatment strategy, especially in case of uncertain haemorrhage patterns on cumputed tomography. The aim of this study was to analyse the safety and efficacy profile of single-stage endovascular treatment of multiple intracranial aneurysms with aneurysmal subarachnoid haemorrhage in the literature and in a retrospective case series.Materials and methodsA systematic review of the present literature was conducted to identify studies related to single-stage endovascular treatment for ≥2 aneurysms; in addition, a retrospective multicentric review was performed. Data on clinical presentation, aneurysm size and location, occlusion rates, intracranial complications and clinical outcome were recorded.ResultsThirteen articles were identified (all little case series) reporting 189 patients harbouring 389 aneurysms. And 85.6% presented with a Hunt-Hess scale 1-3, and 14.4% 4-5. Intracranial complications rate was 11.5%. Baseline and follow-up (20.5 months) occlusion rates were adequate (Raymond-Roy occlusion scale I-II) in 93% and 96.2%, respectively. 81% of patients had favourable clinical outcomes (modified Rankin Scale (mRS) ≤2; Glasgow outcome scale (GOS) 5-4) and 19% poor (mRS 3-6; GOS 3-1). The retrospective database identified 53 patients with 115 aneurysms. Clinical presentation was Hunt-Hess (HH) 1-3/WNFS 1-2 75% and HH 4-5/WNFS 3-5 25%. Intracranial complication rate was 24.5%. Occlusion rate RROC I-II was 78.7% at baseline and 15 months and 90.2% at follow up. Clinical outcome at 3 months was mRS ≤2 68.6% and mRS 3-6 31.4%.ConclusionsSingle-staged endovascular treatment can be feasible, although a higher risk of intraprocedural complications, with clinical presentation being the major factor to influence the outcome.

Indexed as

Endovascular ProceduresIntracranial AneurysmSubarachnoid HemorrhageEmbolization, TherapeuticFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeaneurysmsCoilingsah

Identifiers

PMID37614045
PMCPMC13305001
OpenAlexW4386117424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.