Evidence map›Paper›PMID 37612881›Full record

ArticleAutophagy2023

Membrane localization of LGG-1/GABARAP is dispensable for autophagy in

Romane Leboutet, Céline Largeau, Emmanuel Culetto, Christophe Lefebvre, Thorsten Hoppe, Renaud Legouis

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Autophagy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Romane LeboutetUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC) and INSERM U1280, Gif-sur-Yvette, France.
Céline LargeauUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC) and INSERM U1280, Gif-sur-Yvette, France.
Emmanuel CulettoUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC) and INSERM U1280, Gif-sur-Yvette, France.
Christophe LefebvreUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC) and INSERM U1280, Gif-sur-Yvette, France.
Thorsten HoppeInstitute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Renaud LegouisUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC) and INSERM U1280, Gif-sur-Yvette, France.ORCID 0000-0002-2699-2584
Centre National de la Recherche Scientifique · FRUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most of the functions of LC3/GABARAP in macroautophagy/autophagy are considered to depend on their association with the phagophore membrane through a conjugation to a lipid. Using site-directed mutagenesis, we inhibited the conjugation of LGG-1, the single homolog of GABARAP in

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsAutophagosomesAutophagyMicrotubule-Associated ProteinsCaenorhabditis elegans ProteinsLGG-1 protein, C elegansMicrotubule-Associated ProteinsAtg8autophagosome biogenesisconjugationembryonic developmentlipidationubiquitin-like

Identifiers

PMID37612881
PMCPMC10621266
OpenAlexW4386116550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.