Evidence map›Paper›PMID 37612636›Full record

ReviewBMC infectious diseases2023

Point-of-care testing in private pharmacy and drug retail settings: a narrative review.

Justine Tin Nok Chan, Van Nguyen, Thuy Ngan Tran, Nam Vinh Nguyen, Nga Thi Thuy Do, H Rogier van Doorn, Sonia Lewycka

Open access · goldAbstract readReview
In one paragraph

Review in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Justine Tin Nok ChanFitzwilliam College, University of Cambridge, Cambridge, UK. jtnc2@cam.ac.uk.
Van NguyenDoctor of Medicine Programme, Duke National University of Singapore (NUS) Medical School, Singapore, Singapore.
Thuy Ngan TranOxford University Clinical Research Unit, Hanoi, Vietnam.
Nam Vinh NguyenOxford University Clinical Research Unit, Hanoi, Vietnam.
Nga Thi Thuy DoOxford University Clinical Research Unit, Hanoi, Vietnam.
H Rogier van DoornOxford University Clinical Research Unit, Hanoi, Vietnam.
Sonia LewyckaOxford University Clinical Research Unit, Hanoi, Vietnam.
Oxford University Clinical Research Unit · VNNational University of Singapore · SGUniversity of Antwerp · BEUniversity of Cambridge · GB

Funding

Medical Research Council MR/S001964/1
6 · The paper itself

Abstract

backgroundPoint-of-care testing (POCT) using rapid diagnostic tests for infectious disease can potentially guide appropriate use of antimicrobials, reduce antimicrobial resistance, and economise use of healthcare resources. POCT implementation in private retail settings such as pharmacies and drug shops could lessen the burden on public healthcare. We performed a narrative review on studies of POCTs in low- and middle-income countries (LMICs), and explored uptake, impact on treatment, and feasibility of implementation.

methodsWe searched MEDLINE/PubMed for interventional studies on the implementation of POCT for infectious diseases performed by personnel in private retail settings. Data were extracted and analysed by two independent reviewers.

resultsOf the 848 studies retrieved, 23 were included in the review. Studies were on malaria (19/23), malaria and pneumonia (3/23) or respiratory tract infection (1/23). Nine randomised controlled studies, four controlled, non-randomised studies, five uncontrolled interventions, one interventional pre-post study, one cross-over interventional study and three retrospective analyses of RCTs were included. Study quality was poor. Overall, studies showed that POCT can be implemented successfully, leading to improvements in appropriate treatment as measured by outcomes like adherence to treatment guidelines. Despite some concerns by health workers, customers and shop providers were welcoming of POCT implementation in private retail settings. Main themes that arose from the review included the need for well-structured training with post-training certification covering guidelines for test-negative patients, integrated waste management, community sensitization and demand generation activities, financial remuneration and pricing schemes for providers, and formal linkage to healthcare and support.

conclusionOur review found evidence that POCT can be implemented successfully in private retail settings in LMICs, but comprehensive protocols are needed. High-quality randomised studies are needed to understand POCTs for infectious diseases other than malaria.

Indexed as

PharmaciesPharmacyHealth FacilitiesHumansPoint-of-Care TestingRetrospective StudiesCommunicable diseasesDrug resistanceFeasibility studiesPharmaciesRapid diagnostic tests

Identifiers

PMID37612636
PMCPMC10463283
OpenAlexW4386092597

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.