ArticleBMC urology2023
Prevalence and determinants of decision regret in long-term prostate cancer survivors following radical prostatectomy.
Article in BMC urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- Association between postoperative urinary incontinence severity and anxiety in patients with prostate cancer: A chain mediation analysis of ehealth literacy and pelvic floor muscle training adherence.Asia-Pacific journal of oncology nursing · 2026Article
- Early patient-reported outcomes and decisional regret after robot-assisted radical prostatectomy: A prospective single-center cohort study.Journal of robotic surgery · 2026Observational
- Decision regret in patients with rectal cancer undergoing multimodal therapy.Clinical and translational radiation oncology · 2026Article
- Patient-reported outcomes: active surveillance vs radical therapies in low-risk prostate cancer.BJU international · 2026Article
- Decision regret after reirradiation of the primary site in patients with prostate cancer.Clinical and translational radiation oncology · 2025Article
- Decision regret after external beam radiotherapy and high dose-rate brachytherapy boost for prostate cancer.World journal of urology · 2025Article
- Article
- Treatment decision regret after precision prostatectomy: An analysis of patient-reported outcomes predicting decision regret.BJUI compass · 2025Article
- Short-Term Urinary Incontinence After Radical Prostatectomy Is Still Based on Patients' Age, Nerve-Sparing Approach, and Surgical-Experience, Despite the Higher-Use of Robotic Surgery in 2022 Compared to 2016 Real-World Results of a Large Rehabilitation Center in Germany.Cancer reports (Hoboken, N.J.) · 2024Article
- Association of Patient Comorbidities With Treatment Regret Among Patients With Localized Prostate Cancer - Results From a Population-Based Cohort.Practical radiation oncologyArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with localized prostate cancer (PC) are faced with a wide spectrum of therapeutic options at initial diagnosis. Following radical prostatectomy (RP), PC patients may experience regret regarding their initial choice of treatment, especially when oncological and functional outcomes are poor. Impacts of psychosocial factors on decision regret, especially after long-term follow-up, are not well understood. This study aimed to investigate the prevalence and determinants of decision regret in long-term PC survivors following RP.
methods3408 PC survivors (mean age 78.8 years, SD = 6.5) from the multicenter German Familial PC Database returned questionnaires after an average of 16.5 (SD = 3.8) years following RP. The outcome of decision regret concerning the initial choice of RP was assessed with one item from the Decision Regret Scale. Health-related quality of life (HRQoL), PC-anxiety, PSA-anxiety, as well as anxiety and depressive symptoms were considered for independent association with decision regret via multivariable logistic regression.
results10.9% (373/3408) of PC survivors reported decision regret. Organ-confined disease at RP (OR 1.39, 95%CI 1.02-1.91), biochemical recurrence (OR 1.34, 1.00-1.80), low HRQoL (OR 1.69,1.28-2.24), depressive symptoms (OR 2.32, 1.52-3.53), and prevalent PSA anxiety (OR 1.88,1.17-3.01) were significantly associated with increased risk of decision regret. Shared decision-making reduced the odds of decision regret by 40% (OR 0.59, 0.41-0.86).
conclusionsPC survivors may experience decision regret even after 16 years following RP. Promoting shared decision-making in light of both established and novel, potentially less invasive treatments at initial diagnosis may help mitigate long-term regret. Awareness regarding patients showing depressive symptoms or PSA anxiety should be encouraged to identify patients at risk of decision regret in need of additional psychological support.
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